Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K9 | P80192 | 1/20 | 0.31 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.31 |
| ▸ | PNMT | P11086 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9170496 | 0.85 | PNMT (0.35) | MAP3K9MAP3K11PNMT | |
| Hydrochloric Acid SCHEMBL9166997 | 0.81 | PNMT (0.38) | MAP3K9MAP3K11PNMT | |
| Hydrochloric Acid SCHEMBL7604670 | 0.81 | PNMT (0.37) | MAP3K9MAP3K11PNMT | |
| Hydrochloric Acid SCHEMBL9170485 | 0.81 | PNMT (0.35) | MAP3K9MAP3K11PNMT | |
| Hydrochloric Acid SCHEMBL5348858 | 0.77 | PNMT (0.51) | PNMT | |
| SCHEMBL7607098 | 0.76 | PNMT (0.38) | MAP3K9MAP3K11PNMT | |
| Hydrochloric Acid SCHEMBL9163302 | 0.75 | MAP3K9 (0.33) | MAP3K9MAP3K11PNMT | |
| Hydrochloric Acid SCHEMBL9163450 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL5346821 | 0.75 | PNMT (0.51) | PNMT | |
| Hydrochloric Acid SCHEMBL5347439 | 0.75 | PNMT (0.51) | PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5420320-A | Method for preparing cyclopentadienyl-type ligands and metallocene compounds | PHILLIPS PETROLEUM COMPANY (US) | 1995-05-30 | — | — | US | disclosed |