Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.47 |
| ▸ | ACSL1 | P33121 | 2/20 | 0.46 |
| ▸ | ACSL6 | Q9UKU0 | 2/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9876953 | 0.74 | ALOX5 (0.55) | ALOX5MAPTTDP1L3MBTL1HTR2B | |
| Phenoxazine SCHEMBL906621 | 0.73 | KEAP1 (0.63) | ALOX5FFAR1MAPTFFAR4 | |
| SCHEMBL4894070 | 0.72 | ACSL1 (0.45) | ACSL1ACSL6PDK2TSHRFFAR1 | |
| SCHEMBL27750898 | 0.72 | ALOX5 (0.54) | ALOX5TSHRMAPTHTR2B | |
| SCHEMBL27837918 | 0.71 | ALOX5 (0.50) | ALOX5PDK2MAPTTDP1L3MBTL1 | |
| SCHEMBL31191629 | 0.71 | ALOX5 (0.59) | ALOX5MAPTTDP1L3MBTL1HTR2B | |
| SCHEMBL30539402 | 0.71 | PTPN7 (0.67) | PDK2FFAR1TDP1FFAR4PPARA | |
| SCHEMBL20886118 | 0.71 | PTPN7 (0.67) | PDK2FFAR1TDP1FFAR4PPARA | |
| SCHEMBL21628231 | 0.71 | ALOX5 (0.59) | ALOX5MAPTTDP1L3MBTL1HTR2B | |
| Phenoxazine SCHEMBL6292601 | 0.71 | ALOX5 (0.63) | ALOX5MAPTTDP1L3MBTL1HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274700-B1 | Substrates for hydrolases | BOEHRINGER MANNHEIM GMBH (DE) | 1995-05-31 | — | — | EP | disclosed |
| US-5035998-A | Hydrolase substrates | BOEHRINGER MANNHEIM GMBH (DE) | 1991-07-30 | — | — | US | disclosed |
| US-4900822-A | New hydrolase substrates | BOEHRINGER MANNHEIM GMBH (DE) | 1990-02-13 | — | — | US | disclosed |
| EP-0274700-A1 | Substrates for hydrolases | Roche Diagnostics GmbH (DE) | 1988-07-20 | — | — | EP | disclosed |