Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2772583 | 0.89 | LMNA (0.52) | ESR1ESR2HSD17B10PARP10MAPT | |
| SCHEMBL11347614 | 0.85 | CA1 (0.47) | SENP1ESR1ESR2MAPTKMT2A | |
| SCHEMBL11658327 | 0.84 | RXRA (0.44) | SENP1PARP10MAPTKMT2AMEN1 | |
| SCHEMBL27610798 | 0.77 | SERPINE1 (0.55) | ESR1HSD17B10MAPTMAPK1ALDH1A1 | |
| SCHEMBL11660388 | 0.76 | MEN1 (0.33) | SENP1MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL11660390 | 0.75 | SMN1; SMN2 (0.36) | MAPTKMT2AMEN1MAPK1ALDH1A1 | |
| SCHEMBL11657847 | 0.72 | LOXL2 (0.42) | MAPTKMT2AALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL5889497 | 0.71 | SENP1 (0.47) | SENP1HSD17B10PARP10MAPTKMT2A | |
| SCHEMBL21753716 | 0.71 | PTPN1 (0.39) | HSD17B10MAPK1ALDH1A1HPGDCA1 | |
| SCHEMBL9067587 | 0.71 | PTPN1 (0.39) | HSD17B10KMT2AMEN1MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0386406-B1 | Polyhaloaromatic ester flame retardants for polyolefin resins | ATOCHEM NORTH AMERICA (US) | 1995-05-17 | — | — | EP | disclosed |
| US-5086098-A | Polyhaloaromatic ester flame retardants for polyolefin resins | ATOCHEM NORTH AMERICA, INC. (US) | 1992-02-04 | — | — | US | disclosed |
| US-5043374-A | Improved flow characteristics during melt processing | ATOCHEM NORTH AMERICA, INC. (US) | 1991-08-27 | — | — | US | disclosed |
| EP-0386406-A1 | Polyhaloaromatic ester flame retardants for polyolefin resins | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1990-09-12 | — | — | EP | disclosed |
| US-4927873-A | Halophenyl ester flame retardants for polyphenylene ether resins | PENNWALT CORPORATION (US) | 1990-05-22 | — | — | US | disclosed |
| EP-0333987-A2 | Halogenated polyester flame retardants for polyphenylene ether resins | ATOCHEM NORTH AMERICA, INC. (a Pennsylvania corp.) (US) | 1989-09-27 | — | — | EP | disclosed |
| EP-0333979-A1 | Halophenyl ester flame retardants for polyphenylene ether resins | ATOCHEM NORTH AMERICA, INC. (a Pennsylvania corp.) (US) | 1989-09-27 | — | — | EP | disclosed |