Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL91701 | 0.92 | ALDH1A1 (0.35) | ALDH1A1KMT2AMAPK1MEN1CYP3A4 | |
| SCHEMBL91785 | 0.80 | MAPT (0.35) | ALDH1A1KMT2AMAPK1MEN1CYP3A4 | |
| SCHEMBL9282972 | 0.78 | MAPT (0.49) | ALDH1A1KMT2AMAPK1MEN1CYP3A4 | |
| SCHEMBL13863740 | 0.77 | MAPT (0.44) | ALDH1A1KMT2ALMNAPTK2BRXFP1 | |
| SCHEMBL91661 | 0.77 | KMT2A (0.39) | ALDH1A1KMT2AMAPK1MEN1CYP3A4 | |
| Phosphine SCHEMBL28088577 | 0.77 | MAPT (0.48) | ALDH1A1KMT2AMAPK1MEN1CYP3A4 | |
| SCHEMBL17355723 | 0.76 | KMT2A (0.41) | ALDH1A1KMT2AMAPK1MEN1CYP3A4 | |
| SCHEMBL91672 | 0.75 | MAPT (0.34) | ALDH1A1KMT2AMAPK1MEN1CYP3A4 | |
| SCHEMBL12190248 | 0.74 | KMT2A (0.33) | ALDH1A1KMT2AMEN1HPGDMAPT | |
| SCHEMBL91798 | 0.74 | MAPT (0.36) | ALDH1A1KMT2AMAPK1MEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129002-B2 | Compounds for use in liquid crystal media | MERCK PATENT GMBH (DE) | 2012-03-06 | — | — | US | disclosed |