SCHEMBL9174258

SCHEMBL9174258

COc1cc(C(=O)c2ccccc2)cc(CN(CC(=O)O)CC(=O)O)c1O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 8/20 0.47
BCHE P06276 5/20 0.47
CNR2 P34972 2/20 0.47
MAPT P10636 4/20 0.45
KDM4E B2RXH2 3/20 0.45
HSD17B10 Q99714 2/20 0.45
ALOX15 P16050 1/20 0.45
MAPK1 P28482 1/20 0.45
HPGD P15428 2/20 0.44
LMNA P02545 2/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C19 P33261 1/20 0.44
CYP3A4 P08684 1/20 0.44
RECQL P46063 1/20 0.44
ATM Q13315 1/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA3 P07451 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3973204 0.86 ALDH1A1 (0.45) CNR2MAPTHPGDLMNAATM
SCHEMBL5853906 0.85 GABRA1 (0.44) CNR2MAPTHPGDLMNAATM
SCHEMBL14496266 0.83 PTGS2 (0.47) ACHEBCHEMAPTKDM4EHPGD
SCHEMBL9343741 0.80 CA12 (0.63) CNR2MAPTKDM4EHSD17B10ALOX15
SCHEMBL11355111 0.76 IDO1 (0.50) MAPTKDM4EHSD17B10ALOX15MAPK1
SCHEMBL9000847 0.75 PTGS2 (0.47) MAPTKDM4EMAPK1HPGDLMNA
SCHEMBL21306338 0.74 MEN1 (0.56) ACHEBCHEMAPTL3MBTL1GAA
SCHEMBL5853890 0.74 GABRA1 (0.42) ACHECNR2MAPTLMNAATM
SCHEMBL18359689 0.74 ALOX5 (0.44) MAPTKDM4EALOX15LMNACYP3A4
SCHEMBL10883430 0.71 ALOX5 (0.47) MAPTKDM4ELMNAL3MBTL1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0434262-B1 Phenol derivative and its use in colorimetric analysis of metal ions WAKO PURE CHEM IND LTD (JP) 1995-05-03 EP disclosed