Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 20/20 | 0.58 |
| ▸ | GABRD | O14764 | 20/20 | 0.58 |
| ▸ | GABRA1 | P14867 | 20/20 | 0.58 |
| ▸ | GABRB1 | P18505 | 20/20 | 0.58 |
| ▸ | GABRG2 | P18507 | 20/20 | 0.58 |
| ▸ | GABRB3 | P28472 | 20/20 | 0.58 |
| ▸ | GABRA5 | P31644 | 20/20 | 0.58 |
| ▸ | GABRA3 | P34903 | 20/20 | 0.58 |
| ▸ | GABRA2 | P47869 | 20/20 | 0.58 |
| ▸ | GABRB2 | P47870 | 20/20 | 0.58 |
| ▸ | GABRA4 | P48169 | 20/20 | 0.58 |
| ▸ | GABRE | P78334 | 20/20 | 0.58 |
| ▸ | GABRA6 | Q16445 | 20/20 | 0.58 |
| ▸ | GABRG1 | Q8N1C3 | 20/20 | 0.58 |
| ▸ | GABRG3 | Q99928 | 20/20 | 0.58 |
| ▸ | GABRQ | Q9UN88 | 20/20 | 0.58 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8790587 | 0.94 | GABRP (0.59) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL28942114 | 0.93 | GABRP (0.58) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Fipronil SCHEMBL2469515 | 0.92 | GABRP (0.59) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Fipronil SCHEMBL44222 | 0.92 | GABRP (0.59) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Fipronil SCHEMBL15088 | 0.92 | GABRP (0.59) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Fipronil SCHEMBL29397350 | 0.92 | GABRP (0.59) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Fipronil SCHEMBL7171206 | 0.92 | GABRP (0.59) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Fipronil SCHEMBL3351877 | 0.91 | GABRP (0.58) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL15900783 | 0.88 | GABRP (0.55) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL41972 | 0.87 | GABRP (0.59) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0418016-B1 | N-phenylpyrazole derivatives as insecticides | RHONE POULENC AGRICULTURE (GB) | 1995-05-03 | — | — | EP | disclosed |
| EP-0403309-B1 | N-Phenylpyrazole derivatives | RHONE POULENC AGRICULTURE (GB) | 1994-11-02 | — | — | EP | disclosed |
| EP-0418016-A1 | N-phenylpyrazole derivatives as insecticides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1991-03-20 | — | — | EP | disclosed |
| EP-0403309-A1 | N-Phenylpyrazole derivatives | RHONE-POULENC AGRICULTURE LTD. (GB) | 1990-12-19 | — | — | EP | disclosed |