Fipronil

Fipronil

SCHEMBL3351877

N#Cc1nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c(N)c1[S+]([O-])C(F)(F)F.N#Cc1nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c(N)c1[S+]([O-])C(F)(F)F.S

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRP O00591 20/20 0.58
GABRD O14764 20/20 0.58
GABRA1 P14867 20/20 0.58
GABRB1 P18505 20/20 0.58
GABRG2 P18507 20/20 0.58
GABRB3 P28472 20/20 0.58
GABRA5 P31644 20/20 0.58
GABRA3 P34903 20/20 0.58
GABRA2 P47869 20/20 0.58
GABRB2 P47870 20/20 0.58
GABRA4 P48169 20/20 0.58
GABRE P78334 20/20 0.58
GABRA6 Q16445 20/20 0.58
GABRG1 Q8N1C3 20/20 0.58
GABRG3 Q99928 20/20 0.58
GABRQ Q9UN88 20/20 0.58
NR1I2 O75469 1/20 0.58
LMNA P02545 1/20 0.58
CYP3A4 P08684 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fipronil SCHEMBL44222 0.99 GABRP (0.59) GABRPGABRDGABRA1GABRB1GABRG2
Fipronil SCHEMBL15088 0.99 GABRP (0.59) GABRPGABRDGABRA1GABRB1GABRG2
Fipronil SCHEMBL29397350 0.99 GABRP (0.59) GABRPGABRDGABRA1GABRB1GABRG2
Fipronil SCHEMBL7171206 0.99 GABRP (0.59) GABRPGABRDGABRA1GABRB1GABRG2
Fipronil SCHEMBL2469515 0.99 GABRP (0.59) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL14094912 0.92 GABRP (0.53) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL15329374 0.92 GABRP (0.53) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL8790587 0.92 GABRP (0.59) GABRPGABRDGABRA1GABRB1GABRG2
Fipronil SCHEMBL21693736 0.92 GABRP (0.53) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL9174428 0.91 GABRP (0.58) GABRPGABRDGABRA1GABRB1GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121577800-A Non-targeted screening multi-pesticide residue detection method based on high-resolution mass spectrum 常州市食品药品纤维质量监督检验中心(常州市粮油质量监督检测站、常州纤维检验所) 2026-02-27 CN claimed
CN-118566374-A Method for detecting pesticide and metabolite residues in soil 河北省农药检定监测总站 2024-08-30 CN claimed
CN-118243833-A Method for simultaneously determining multiple pesticide residues in tea by QuEChERS-GC-MS/MS method 广东中检达元检测技术有限公司 2024-06-25 CN claimed
CN-116908338-A Method for simultaneously measuring 110 pesticide residues in various tropical fruits 中国热带农业科学院三亚研究院 2023-10-20 CN claimed
CN-115228449-B Different-pore covalent organic framework sponge composite material and preparation method and application thereof 农业农村部环境保护科研监测所 2023-08-01 CN claimed
CN-115228449-A Heteroporous covalent organic framework sponge composite material and preparation method and application thereof 农业农村部环境保护科研监测所 2022-10-25 CN claimed
CN-112034053-B Method for detecting pesticide residues in traditional Chinese medicinal materials 中国农业科学院农产品加工研究所 2022-06-14 CN claimed
CN-113945656-A Method for detecting pesticide and metabolite residues thereof in traditional Chinese medicinal materials 中国农业科学院农产品加工研究所 2022-01-18 CN claimed
CN-112305131-B GC-Orbitrap-MS screening and analyzing method for pesticide residues in animal derived food 中国农业科学院农业质量标准与检测技术研究所 2021-09-21 CN claimed
CN-112305131-A GC-Orbitrap-MS screening and analyzing method for pesticide residues in animal derived food 中国农业科学院农业质量标准与检测技术研究所 2021-02-02 CN claimed
CN-112034053-A Method for detecting pesticide residues in traditional Chinese medicinal materials 中国农业科学院农产品加工研究所 2020-12-04 CN claimed
CN-110702858-A Method for testing deodorization effect of super absorbent resin 宜兴丹森科技有限公司 2020-01-17 CN claimed
CN-121577800-A Non-targeted screening multi-pesticide residue detection method based on high-resolution mass spectrum 常州市食品药品纤维质量监督检验中心(常州市粮油质量监督检测站、常州纤维检验所) 2026-02-27 CN disclosed
EP-4644553-A9 NON-NUCLEIC ACID TARGET DETECTION METHOD BASED ON SPLIT CAS PROTEIN AND USE THEREOF Shanghai Tolo Biotechnology Company Limited (CN) 2025-12-17 EP disclosed
EP-4644553-A1 NON-NUCLEIC ACID TARGET DETECTION METHOD BASED ON SPLIT CAS PROTEIN AND USE THEREOF Shanghai Tolo Biotechnology Company Limited (CN) 2025-11-05 EP disclosed
US-20250281926-A1 SAMPLE MANIPULATION AND ASSAY WITH RAPID TEMPERATURE CHANGE ESSENLIX CORPORATION (US) 2025-09-11 US disclosed
US-20050234119-A1 Antiparasitical agents and methods for treating, preventing and controlling external parasites in animals MERIAL LIMITED 2005-10-20 US disclosed
US-6797724-B2 TO ELIMINATE BOOPHILUS MICROPLUS IN CATTLE AND LICE AND BLOWFLY IN SHEEP MERIAL (FR) 2004-09-28 US disclosed
US-20020155147-A1 Direct pour-on antiparasitic skin solution and methods for treating, preventing and controlling myasis MERIAL (FR) 2002-10-24 US disclosed
US-6413542-B1 TOPICAL SOLUTION OF A PYRAZOLE COMPOUND OF GIVEN FORMULA; CONTROLLING TICKS: ELIMINATION OF BOOPHILUS MICROPLUS IN LESS THAN 2 DAYS, FOR CATTLE, SHEEP MERIAL (FR) 2002-07-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050234119-A1 Antiparasitical agents and methods for treating, preventing and controlling external parasites in animals CAT, ACHE, CTSA GABRP 1246/4885GABRD 1147/4885GABRA1 713/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.