Fipronil

Fipronil

SCHEMBL15088

N#Cc1nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c(N)c1[S+]([O-])C(F)(F)F

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRP O00591 20/20 0.59
GABRD O14764 20/20 0.59
GABRA1 P14867 20/20 0.59
GABRB1 P18505 20/20 0.59
GABRG2 P18507 20/20 0.59
GABRB3 P28472 20/20 0.59
GABRA5 P31644 20/20 0.59
GABRA3 P34903 20/20 0.59
GABRA2 P47869 20/20 0.59
GABRB2 P47870 20/20 0.59
GABRA4 P48169 20/20 0.59
GABRE P78334 20/20 0.59
GABRA6 Q16445 20/20 0.59
GABRG1 Q8N1C3 20/20 0.59
GABRG3 Q99928 20/20 0.59
GABRQ Q9UN88 20/20 0.59
NR1I2 O75469 1/20 0.59
LMNA P02545 1/20 0.59
CYP3A4 P08684 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fipronil SCHEMBL44222 1.00 GABRP (0.59) GABRPGABRDGABRA1GABRB1GABRG2
Fipronil SCHEMBL2469515 1.00 GABRP (0.59) GABRPGABRDGABRA1GABRB1GABRG2
Fipronil SCHEMBL29397350 1.00 GABRP (0.59) GABRPGABRDGABRA1GABRB1GABRG2
Fipronil SCHEMBL7171206 1.00 GABRP (0.59) GABRPGABRDGABRA1GABRB1GABRG2
Fipronil SCHEMBL3351877 0.99 GABRP (0.58) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL14094912 0.93 GABRP (0.53) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL15329374 0.93 GABRP (0.53) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL8790587 0.93 GABRP (0.59) GABRPGABRDGABRA1GABRB1GABRG2
Fipronil SCHEMBL21693736 0.93 GABRP (0.53) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL9174428 0.92 GABRP (0.58) GABRPGABRDGABRA1GABRB1GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 47674 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12635691-B2 Fipronil containing insecticide gels HENKEL AG & CO. KGAA (DE) 2026-05-26 US claimed
CN-224285280-U Fipronil filter cake drying and crushing device Zhejiang Fanghua Chemical Co.,Ltd. (CN) 2026-05-26 CN claimed
CN-224270229-U Fipronil solid extraction device Zhejiang Fanghua Chemical Co.,Ltd. (CN) 2026-05-26 CN claimed
CN-122056270-A Pesticide suspension concentrate and fertilizer composition thereof 诺力昂化学品国际有限公司 2026-05-19 CN claimed
CN-122036637-A Polymorphs 先正达农作物保护股份公司 2026-05-15 CN claimed
CN-122004191-A Hydraulic engineering termite control agent high-pressure grouting device and agent composition thereof 湖北楚天蕙兰白蚁防治有限公司 2026-05-12 CN claimed
EP-4734762-A1 BAIT COMPOSITIONS FMC Corporation (US) 2026-05-06 EP claimed
EP-4255391-B1 LUMINOL FOR USE IN THE TREATMENT OF SEQUELAE OF A SARS-COV-2 INFECTION METRIOPHARM AG (CH) 2026-05-06 EP claimed
EP-3324955-B1 COMPOSITION COMPRISING FIPRONIL AND DINOTEFURAN FOR USE IN AMETHOD OF CONTROLLING FLEAS IN NON HUMAN MAMMALS CEVA SANTE ANIMALE (FR) 2026-04-29 EP claimed
EP-3175865-B1 FUNCTIONAL PARTICLES, PROCESS TO OBTAIN THEM, AND THEIR APPLICATIONS SMART INOVATION LDA (PT) 2026-04-15 EP claimed
WO-1996016544-A2 EMULSIFIABLE COMPOSITION FOR THE CONTROL OF INSECTS RHONE-POULENC AGROCHIMIE (FR) 1996-06-06 WO claimed
US-5516787-A AN N-ARYL PYRAZOLE COMPOUND AND A CHRYSANTHEMATE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-05-14 US claimed
WO-1995033380-A1 SYNERGISTIC COMPOSITION CIBA-GEIGY AG (CH) 1995-12-14 WO claimed
CN-1108043-A Combinations of a fungicide containing an azole group with an insecticide containing a pyrazole, pyrrole or phenylimidazole group RHONE POULENC AGROCHIMIE (FR) 1995-09-13 CN claimed
WO-1995022902-A1 SYNERGISTIC TERMITICIDAL COMPOSITION OF PYRETHROID AND N-PHENYL-PYRAZOLE RHONE-POULENC AGROCHIMIE (FR) 1995-08-31 WO claimed
WO-1995012314-A1 COMBINATIONS OF A FUNGICIDE HAVING AN AZOLE GROUP WITH AN INSECTICIDE HAVING A PYRAZOLE, PYRROLE OR PHENYLIMIDAZOLE GROUP RHONE POULENC AGROCHIMIE (FR) 1995-05-11 WO claimed
EP-0435609-B1 Arthropodicidal composition comprising thiodicarb and a phenylpyrazole RHONE POULENC AGRICULTURE (GB) 1994-02-23 EP claimed
US-5270043-A Arthropodicidal composition comprising thiodicarb and a phenylpyrazole RHONE-POULENC AGRICULTURE LTD. (GB) 1993-12-14 US claimed
US-5232940-A Controlling insects, plant nematodes, helminths, protozoa BASF AGRO B.V., ARNHEM (NL), WADENSWIL-BRANCH (CH) 1993-08-03 US claimed
EP-0435609-A1 Arthropodicidal composition comprising thiodicarb and a phenylpyrazole RHONE-POULENC AGRICULTURE LTD. (GB) 1991-07-03 EP claimed