Fipronil

Fipronil

SCHEMBL44222

N#Cc1nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c(N)c1[S@+]([O-])C(F)(F)F

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRP O00591 20/20 0.59
GABRD O14764 20/20 0.59
GABRA1 P14867 20/20 0.59
GABRB1 P18505 20/20 0.59
GABRG2 P18507 20/20 0.59
GABRB3 P28472 20/20 0.59
GABRA5 P31644 20/20 0.59
GABRA3 P34903 20/20 0.59
GABRA2 P47869 20/20 0.59
GABRB2 P47870 20/20 0.59
GABRA4 P48169 20/20 0.59
GABRE P78334 20/20 0.59
GABRA6 Q16445 20/20 0.59
GABRG1 Q8N1C3 20/20 0.59
GABRG3 Q99928 20/20 0.59
GABRQ Q9UN88 20/20 0.59
NR1I2 O75469 1/20 0.59
LMNA P02545 1/20 0.59
CYP3A4 P08684 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fipronil SCHEMBL2469515 1.00 GABRP (0.59) GABRPGABRDGABRA1GABRB1GABRG2
Fipronil SCHEMBL15088 1.00 GABRP (0.59) GABRPGABRDGABRA1GABRB1GABRG2
Fipronil SCHEMBL29397350 1.00 GABRP (0.59) GABRPGABRDGABRA1GABRB1GABRG2
Fipronil SCHEMBL7171206 1.00 GABRP (0.59) GABRPGABRDGABRA1GABRB1GABRG2
Fipronil SCHEMBL3351877 0.99 GABRP (0.58) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL14094912 0.93 GABRP (0.53) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL15329374 0.93 GABRP (0.53) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL8790587 0.93 GABRP (0.59) GABRPGABRDGABRA1GABRB1GABRG2
Fipronil SCHEMBL21693736 0.93 GABRP (0.53) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL9174428 0.92 GABRP (0.58) GABRPGABRDGABRA1GABRB1GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7836630-B2 Method of protecting seeds treated with a phytotoxic agent MONSANTO TECHNOLOGY LLC (US) 2010-11-23 US claimed
US-20100179196-A1 COMPOSITIONS AND METHODS FOR DEPLOYING A TRANSGENIC REFUGE AS A SEED BLEND PERSHING JAY C 2010-07-15 US claimed
EP-1566996-B1 METHOD OF PROTECTING SEEDS TREATED WITH A PHYTOTOXIC AGENT MONSANTO TECHNOLOGY LLC (US) 2009-11-11 EP claimed
WO-2004049778-A9 METHOD OF PROTECTING SEEDS TREATED WITH A PHYTOTOXIC AGENT MONSANTO TECHNOLOGY LLC (US) 2005-09-22 WO claimed
US-20050197251-A1 Method of controlling the release of agricultural active ingredients from treated plant seeds MONSANTO TECHNOLOGY, L.L.C. (US) 2005-09-08 US claimed
EP-1566996-A1 METHOD OF PROTECTING SEEDS TREATED WITH A PHYTOTOXIC AGENT Monsanto Technology LLC (US) 2005-08-31 EP claimed
US-20040259732-A1 Treatment of plants and plant propagation materials with an antioxidant to improve plant health and/or yield MONSANTO TECHNOLOGY, L.L.C. 2004-12-23 US claimed
WO-2004095926-A2 TREATMENT OF PLANTS AND PLANT PROPAGATION MATERIALS WITH AN ANTIOXIDANT TO IMPROVE PLANT HEALTH AND/OR YIELD MONSANTO TECHNOLOGY, LLC (US) 2004-11-11 WO claimed
US-20040118040-A1 Method of protecting seeds treated with a phytotoxic agent MONSANTO TECHNOLOGY, L.L.C. 2004-06-24 US claimed
WO-2004049778-A1 METHOD OF PROTECTING SEEDS TREATED WITH A PHYTOTOXIC AGENT MONSANTO TECHNOLOGY, LLC (US) 2004-06-17 WO claimed
EP-1168920-B1 (S)-ENANTIOMER ENRICHED FIPRONIL COMPOSITION MERIAL SAS (FR) 2003-06-18 EP claimed
US-6551962-B1 Blending transgenic pest resistant crop seeds with non-transgenic refuge crop seeds; ensuring a uniform mixture of transgenic and non-transgenic crop seeds is provided; planting mix in field to protect corn against feeding damage by pests MONSANTO TECHNOLOGY LLC 2003-04-22 US claimed
US-20030018992-A1 Method for reducing pest damage to corn by treating transgenic corn seeds with pesticide MONSANTO TECHNOLOGY, L.L.C. 2003-01-23 US claimed
JP-2002542173-A 2002-12-10 JP claimed
WO-2002080675-A1 TREATED PLANT SEEDS WITH CONTROLLED RELEASE OF ACTIVE AGENTS MONSANTO TECHNOLOGY, LLC (US) 2002-10-17 WO claimed
US-20020134012-A1 Method of controlling the release of agricultural active ingredients from treated plant seeds MONSANTO TECHNOLOGY, L.L.C. 2002-09-26 US claimed
US-20020082289-A1 Intermediates for pesticidal composition comprising enantiomeric form of fipronil HUBER SCOT KEVIN (US) 2002-06-27 US claimed
US-6346542-B1 Pesticidal composition comprising enantiomeric form of fipronil AVENTIS CROPSCIENCE S.A. (FR) 2002-02-12 US claimed
EP-1168920-A1 (S)-ENANTIOMER ENRICHED FIPRONIL COMPOSITION AVENTIS CROPSCIENCE S.A. (FR) 2002-01-09 EP claimed
WO-2000062616-A1 (S)-ENANTIOMER ENRICHED FIPRONIL COMPOSITION AVENTIS CROPSCIENCE S.A. (FR) 2000-10-26 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020082289-A1 Intermediates for pesticidal composition comprising enantiomeric form of fipronil POR, CYP2E1, FIP1L1 GABRP 126/4885GABRD 471/4885GABRA1 554/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.