SCHEMBL9174451

SCHEMBL9174451

BrCC(OC(CBr)c1ccccc1)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.39
TAAR1 Q96RJ0 1/20 0.39
GSR P00390 1/20 0.38
SLC6A4 P31645 2/20 0.37
DPP4 P27487 2/20 0.36
TSHR P16473 2/20 0.36
TRPA1 O75762 1/20 0.36
ALDH1A1 P00352 1/20 0.36
F2 P00734 1/20 0.36
HRH1 P35367 1/20 0.36
MTOR P42345 1/20 0.36
RAB9A P51151 1/20 0.36
GRM7 Q14831 1/20 0.36
CHRNB2 P17787 1/20 0.35
CHRNA4 P43681 1/20 0.35
CES2 O00748 1/20 0.34
CES1 P23141 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28653431 0.87 TAAR1 (0.39) HTR2ATAAR1GSRSLC6A4TRPA1
SCHEMBL10011300 0.85 HTR2A (0.39) HTR2ATAAR1GSRSLC6A4DPP4
SCHEMBL2067075 0.81 SLC6A4 (0.39) HTR2ATAAR1GSRSLC6A4TSHR
SCHEMBL2067077 0.81 SLC6A4 (0.39) HTR2ATAAR1GSRSLC6A4TSHR
SCHEMBL3053696 0.81 SLC6A4 (0.39) HTR2ATAAR1GSRSLC6A4TSHR
SCHEMBL6153356 0.78 HRH1 (0.38) HTR2AGSRSLC6A4TSHRHRH1
SCHEMBL10986680 0.78 L3MBTL1 (0.40) HTR2ASLC6A4TSHRHRH1
SCHEMBL8715494 0.76 CHRNB2 (0.37) HTR2ATAAR1GSRSLC6A4DPP4
SCHEMBL6044546 0.76 TAAR1 (0.36) TAAR1SLC6A4TRPA1ALDH1A1HRH1
SCHEMBL4590208 0.76 SIGMAR1 (0.39) HTR2AGSRSLC6A4HRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0522069-B1 METHOD TO IMPART COFFEE STAIN RESISTANCE TO POLYAMIDE TEXTILE SUBSTRATES ALLIED SIGNAL INC (US) 1995-05-24 EP disclosed
US-5364541-A Method to impart coffee stain resistance to polyamide textile substrates ALLIEDSIGNAL INC. 1994-11-15 US disclosed
US-5359010-A Phenoxy- or naphthyloxy-acrylic acid ester-maleic acid copolymers as antisoilants for nylon carpets or upholstery ALLIEDSIGNAL INC. (US) 1994-10-25 US disclosed
EP-0540469-A1 Derivatives of the macrolide sopharen C and their use as microbicides Gesellschaft für Biotechnologische Forschung mbH (GBF) (DE) 1993-05-05 EP disclosed
US-5206053-A Terpolymer of phenyl vinyl ether, 2-(4-hydroxymethyl-phenoxy) ethyl vinyl ether and maleic anhydride ALLIED-SIGNAL INC. (US) 1993-04-27 US disclosed
EP-0522069-A1 METHOD TO IMPART COFFEE STAIN RESISTANCE TO POLYAMIDE TEXTILE SUBSTRATES. ALLIED SIGNAL INC (US) 1993-01-13 EP disclosed
US-5135774-A Using polymer protective coatings ALLIED-SIGNAL INC. (US) 1992-08-04 US disclosed
US-5118551-A Method to impart stain resistance to polyamide textile substrates ALLIED-SIGNAL INC. (US) 1992-06-02 US disclosed
WO-1991014818-A1 METHOD TO IMPART COFFEE STAIN RESISTANCE TO POLYAMIDE TEXTILE SUBSTRATES ALLIED-SIGNAL INC. (US) 1991-10-03 WO disclosed