Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.56 |
| ▸ | ACE | P12821 | 6/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9175072 | 1.00 | HDAC8 (0.56) | HDAC8ACEABCB11MMP2 | |
| Bromide SCHEMBL7342024 | 0.99 | HDAC8 (0.55) | HDAC8ACEABCB11MMP2 | |
| Bromide SCHEMBL7342017 | 0.99 | HDAC8 (0.55) | HDAC8ACEABCB11MMP2 | |
| SCHEMBL11279169 | 0.84 | ACE (0.53) | HDAC8ACEABCB11MMP2 | |
| SCHEMBL11260996 | 0.82 | ACE (0.53) | HDAC8ACEABCB11MMP2 | |
| SCHEMBL11212483 | 0.82 | ACE (0.53) | ACEABCB11 | |
| SCHEMBL11216048 | 0.81 | ACE (0.53) | HDAC8ACEABCB11MMP2 | |
| SCHEMBL11216045 | 0.81 | ACE (0.53) | HDAC8ACEABCB11MMP2 | |
| SCHEMBL14776984 | 0.79 | MMP2 (0.49) | HDAC8ACEABCB11MMP2 | |
| SCHEMBL11266964 | 0.79 | REN (0.56) | HDAC8ACEABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0050800-B2 | Carboxyalkyl dipeptides, processes for their production and pharmaceutical compositions containing them | SCHERING CORP (US) | 1995-06-07 | — | — | EP | disclosed |
| EP-0050800-B1 | CARBOXYALKYL DIPEPTIDES, PROCESSES FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING CORPORATION (US) | 1986-06-18 | — | — | EP | disclosed |