Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 3/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.30 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.30 |
| ▸ | NT5E | P21589 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL91739 | 0.88 | FFAR4 (0.31) | FFAR4CYP11B1CYP11B2NT5E | |
| SCHEMBL91839 | 0.84 | FFAR4 (0.33) | SCN5AFFAR4HSD17B1HSD17B2NT5E | |
| SCHEMBL91734 | 0.82 | AR (0.35) | ARHSD17B1HSD17B2 | |
| SCHEMBL91808 | 0.82 | AR (0.31) | AR | |
| SCHEMBL91827 | 0.80 | LMNA (0.34) | AR | |
| SCHEMBL91723 | 0.80 | FFAR4 (0.32) | FFAR4 | |
| SCHEMBL91721 | 0.76 | S1PR1 (0.38) | ARPGRFFAR4CYP11B1CYP11B2 | |
| SCHEMBL91711 | 0.74 | HSD17B1 (0.36) | FFAR4CYP11B1CYP11B2HSD17B1HSD17B2 | |
| SCHEMBL91725 | 0.73 | NR1H4 (0.35) | — | |
| SCHEMBL91743 | 0.71 | FFAR4 (0.31) | FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129002-B2 | Compounds for use in liquid crystal media | MERCK PATENT GMBH (DE) | 2012-03-06 | — | — | US | disclosed |