Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.32 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | NT5E | P21589 | 1/20 | 0.32 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL91739 | 0.84 | FFAR4 (0.31) | FFAR4NT5E | |
| SCHEMBL91756 | 0.84 | AR (0.33) | FFAR4HSD17B1HSD17B2NT5ESCN5A | |
| SCHEMBL91733 | 0.81 | ESR1 (0.37) | ESR1ESR2HSD17B1HSD17B2ERN1 | |
| SCHEMBL91877 | 0.81 | PTGDR2 (0.32) | — | |
| SCHEMBL91721 | 0.79 | S1PR1 (0.38) | FFAR4HSD17B1HSD17B2 | |
| SCHEMBL91791 | 0.78 | KIF11 (0.35) | ESR1ESR2ERN1SCN10A | |
| SCHEMBL91723 | 0.78 | FFAR4 (0.32) | FFAR4ESR1ESR2 | |
| SCHEMBL91779 | 0.77 | ERN1 (0.39) | FFAR4ESR1ESR2HSD17B1HSD17B2 | |
| SCHEMBL91711 | 0.76 | HSD17B1 (0.36) | FFAR4ESR1ESR2HSD17B1HSD17B2 | |
| SCHEMBL12433464 | 0.72 | LMNA (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129002-B2 | Compounds for use in liquid crystal media | MERCK PATENT GMBH (DE) | 2012-03-06 | — | — | US | disclosed |