Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL91666 | 0.95 | RAPGEF4 (0.34) | RAPGEF4MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL91660 | 0.92 | RAPGEF4 (0.33) | RAPGEF4MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL91702 | 0.80 | — | — | |
| SCHEMBL91684 | 0.77 | RAPGEF4 (0.32) | RAPGEF4FFAR1 | |
| SCHEMBL91685 | 0.76 | — | — | |
| SCHEMBL91693 | 0.75 | RAPGEF4 (0.34) | RAPGEF4 | |
| SCHEMBL91658 | 0.73 | RAPGEF4 (0.33) | RAPGEF4 | |
| SCHEMBL21021433 | 0.73 | PTGS2 (0.45) | RAPGEF4 | |
| SCHEMBL13087002 | 0.73 | NISCH (0.43) | RAPGEF4 | |
| SCHEMBL91798 | 0.72 | MAPT (0.36) | FFAR1MEN1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129002-B2 | Compounds for use in liquid crystal media | MERCK PATENT GMBH (DE) | 2012-03-06 | — | — | US | disclosed |