Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.44 |
| ▸ | RAPGEF4 | Q8WZA2 | 3/20 | 0.41 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.40 |
| ▸ | PIM1 | P11309 | 2/20 | 0.40 |
| ▸ | FLT3 | P36888 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.40 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | PAK4 | O96013 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30601207 | 0.87 | PTGS2 (0.45) | PTGS2PTGS1DAPK3NTRK1PIM1 | |
| SCHEMBL13087002 | 0.83 | NISCH (0.43) | PTGS2RAPGEF4LCKKITSRC | |
| SCHEMBL30507311 | 0.83 | PTGS2 (0.47) | PTGS2PTGS1DAPK3NTRK1PIM1 | |
| SCHEMBL30122516 | 0.79 | ALDH1A1 (0.39) | PTGS2PTGS1RAPGEF4 | |
| SCHEMBL5423580 | 0.78 | GRIA1 (0.44) | PTGS2PTGS1DAPK3NTRK1PIM1 | |
| SCHEMBL19730994 | 0.78 | ALDH1A1 (0.43) | RAPGEF4LCKKITSRC | |
| SCHEMBL30507312 | 0.77 | ACHE (0.48) | PTGS2PTGS1RAPGEF4 | |
| Methyl Alcohol SCHEMBL11123696 | 0.77 | DAPK3 (0.42) | PTGS2PTGS1DAPK3NTRK1PIM1 | |
| SCHEMBL91695 | 0.76 | ERN1 (0.47) | LCKKITSRC | |
| SCHEMBL91666 | 0.76 | RAPGEF4 (0.34) | PTGS2RAPGEF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023134698-A1 | PYRIDAZINE-1(6H)-6-OXO COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 深圳信立泰药业股份有限公司 | 2023-07-20 | — | — | WO | disclosed |
| US-20190152919-A1 | COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME | LG CHEM, LTD. (KR) | 2019-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190152919-A1 | COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME | OR10J3, ETV6, ESR1 | PTGS2 3724/4885PTGS1 4519/4885RAPGEF4 3208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.