Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.65 |
| ▸ | HPGD | P15428 | 3/20 | 0.65 |
| ▸ | BRAF | P15056 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | GPR18 | Q14330 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.47 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.47 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.47 |
| ▸ | TNF | P01375 | 1/20 | 0.47 |
| ▸ | G6PD | P11413 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7441558 | 0.87 | KDM4E (0.56) | KDM4EHPGDBRAFLMNASMN1; SMN2 | |
| SCHEMBL556003 | 0.87 | KDM4E (0.55) | KDM4EHPGDBRAFLMNASMN1; SMN2 | |
| SCHEMBL7430972 | 0.85 | KDM4E (0.53) | KDM4EHPGDBRAFLMNASMN1; SMN2 | |
| SCHEMBL7434786 | 0.83 | HPGD (0.51) | KDM4EHPGDBRAFLMNASMN1; SMN2 | |
| SCHEMBL28749924 | 0.80 | TSHR (0.50) | KDM4EHPGDLMNASMN1; SMN2KMT2A | |
| SCHEMBL9707747 | 0.80 | KDM4E (0.44) | KDM4EHPGDGPR18 | |
| SCHEMBL6348692 | 0.79 | BRAF (0.72) | KDM4EBRAFKMT2APOLBMAPT | |
| SCHEMBL28094075 | 0.77 | ALDH1A1 (0.41) | KDM4EHPGDLMNAMAPTALDH1A1 | |
| SCHEMBL16028369 | 0.76 | GPR18 (0.55) | KDM4EHPGDBRAFSMN1; SMN2KMT2A | |
| SCHEMBL27399997 | 0.75 | ALDH1A1 (0.42) | KDM4EHPGDLMNAKMT2AGPR18 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5393755-A | Hypotensive agents, enzyme inhibitors | SCHERING CORPORATION (US) | 1995-02-28 | — | — | US | disclosed |