Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.33 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | PELP1 | Q8IZL8 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27090240 | 0.80 | BACE1 (0.40) | ALDH1A1HTTELANENPSR1TDP1 | |
| SCHEMBL4046263 | 0.78 | CASP6 (0.53) | ALDH1A1ELANELMNA | |
| SCHEMBL8185669 | 0.72 | GPR35 (0.51) | ALDH1A1TDP1L3MBTL1HPGDLMNA | |
| SCHEMBL8781783 | 0.72 | ELANE (0.60) | ELANENPSR1L3MBTL1HPGDLMNA | |
| SCHEMBL9172865 | 0.72 | NPC1 (0.41) | ALDH1A1HTTL3MBTL1 | |
| SCHEMBL9178124 | 0.70 | ELANE (0.46) | ELANEL3MBTL1 | |
| SCHEMBL521667 | 0.70 | ALDH1A1 (0.38) | ALDH1A1HTTTDP1L3MBTL1CHEK1 | |
| SCHEMBL18823473 | 0.69 | ELANE (0.49) | ALDH1A1HTTELANEL3MBTL1LMNA | |
| SCHEMBL5886755 | 0.69 | ALDH1A1 (0.52) | ALDH1A1HTTNPSR1TDP1L3MBTL1 | |
| SCHEMBL14568010 | 0.69 | TSHR (0.38) | ALDH1A1HTTTDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525626-B1 | Compounds containing acid-cleavable protective groups and positive-working radiation-sensitive compositions prepared using these compounds | HOECHST AG (DE) | 1995-06-14 | — | — | EP | disclosed |
| EP-0525626-A1 | Compounds containing acid-cleavable protective groups and positive-working radiation-sensitive compositions prepared using these compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-02-03 | — | — | EP | disclosed |