Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.52 |
| ▸ | ACACB | O00763 | 12/20 | 0.49 |
| ▸ | ACACA | Q13085 | 6/20 | 0.45 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8203531 | 0.86 | ALOX5 (0.67) | ALOX5ACACBACACAHAO1SMN1; SMN2 | |
| SCHEMBL9049055 | 0.81 | ALOX5 (0.79) | ALOX5ACACBACACA | |
| SCHEMBL9422278 | 0.74 | ALOX5 (0.56) | ALOX5ACACBACACAHAO1SMN1; SMN2 | |
| SCHEMBL5942804 | 0.73 | ACACB (0.78) | ACACBACACA | |
| SCHEMBL9051127 | 0.72 | ALOX5 (0.45) | ALOX5HAO1 | |
| SCHEMBL5942969 | 0.72 | ACACB (0.70) | ALOX5ACACBACACAMTNR1BPTGS1 | |
| SCHEMBL5943325 | 0.71 | ACACB (0.62) | ACACBACACASMN1; SMN2 | |
| SCHEMBL8198208 | 0.70 | ALOX5 (0.61) | ALOX5ACACBACACAHAO1MTNR1B | |
| SCHEMBL920824 | 0.70 | PDE4A (0.46) | SMN1; SMN2 | |
| SCHEMBL9176290 | 0.69 | ALOX5 (0.49) | ALOX5ACACBACACAHAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0652864-A1 | HYDROXAMIC ACID DERIVATIVES AND THEIR USE AS ANTI-INFLAMMATORY COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1995-05-17 | — | — | EP | claimed |
| WO-1994002448-A1 | HYDROXAMIC ACID DERIVATIVES AND THEIR USE AS ANTI-INFLAMMATORY COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-02-03 | — | — | WO | claimed |