Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5572477 | 0.90 | CA2 (0.32) | KDM4EL3MBTL1HTTSLC6A4CACNA1F | |
| SCHEMBL9563493 | 0.89 | TAAR1 (0.43) | KDM4EHTTSLC6A4CHRM2CHRM1 | |
| SCHEMBL9563491 | 0.89 | TAAR1 (0.43) | KDM4EHTTSLC6A4CHRM2CHRM1 | |
| SCHEMBL9179092 | 0.86 | ADRB2 (0.38) | CACNA1FCHRM2CHRM1ADRA2BCHRM3 | |
| SCHEMBL9179086 | 0.86 | ADRB2 (0.38) | CACNA1FCHRM2CHRM1ADRA2BCHRM3 | |
| SCHEMBL14984000 | 0.81 | GSR (0.44) | L3MBTL1SLC6A4SLC6A3AOC3CA2 | |
| SCHEMBL8405099 | 0.81 | GSR (0.44) | L3MBTL1SLC6A4SLC6A3AOC3CA2 | |
| SCHEMBL3386535 | 0.81 | TAAR1 (0.41) | SLC6A4SLC6A3TAAR1AOC3CA2 | |
| SCHEMBL1739510 | 0.81 | GSR (0.44) | L3MBTL1SLC6A4SLC6A3AOC3CA2 | |
| SCHEMBL3386613 | 0.81 | TAAR1 (0.41) | SLC6A4SLC6A3TAAR1AOC3CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5412119-A | Method of preparing vicinal aminoalcohols | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1995-05-02 | — | — | US | disclosed |
| EP-0554933-A1 | Method of preparing vicinal aminoalcohols | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1993-08-11 | — | — | EP | disclosed |