Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 7/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 5/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 12/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9183459 | 0.89 | AGTR1 (0.36) | AGTR1AGTR2 | |
| SCHEMBL9183424 | 0.80 | AGTR1 (0.36) | AGTR1AGTR2 | |
| SCHEMBL9486277 | 0.80 | LTB4R2 (0.44) | AGTR1AGTR2LTB4R2 | |
| SCHEMBL9179727 | 0.72 | AGTR1 (0.38) | AGTR1AGTR2 | |
| SCHEMBL8092930 | 0.70 | LTB4R2 (0.49) | AGTR1LTB4R2 | |
| SCHEMBL9285111 | 0.67 | AGTR1 (0.44) | AGTR1AGTR2 | |
| SCHEMBL9263749 | 0.67 | AGTR1 (0.41) | AGTR1AGTR2LTB4R2 | |
| SCHEMBL8700930 | 0.66 | LTB4R2 (0.37) | AGTR1AGTR2LTB4R2 | |
| SCHEMBL9263754 | 0.66 | AGTR1 (0.44) | AGTR1AGTR2 | |
| SCHEMBL18425480 | 0.66 | LTB4R2 (0.69) | AGTR1LTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5405964-A | Angiotensin antagonist | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-04-11 | — | — | US | disclosed |
| EP-0595151-A2 | Imidazopyridine derivates as antagonists of angiotensin II | MERCK PATENT GmbH (DE) | 1994-05-04 | — | — | EP | disclosed |