Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 4/20 | 0.44 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.44 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9479341 | 0.89 | AGTR1 (0.46) | AGTR1AGTR2MAPTPOLB | |
| SCHEMBL9263754 | 0.85 | AGTR1 (0.44) | AGTR1AGTR2BDKRB1 | |
| SCHEMBL9479326 | 0.85 | AGTR1 (0.40) | AGTR1AGTR2MAPTLMNAFLT3 | |
| SCHEMBL9478800 | 0.80 | AGTR1 (0.38) | AGTR1AGTR2MAPTPOLBLMNA | |
| SCHEMBL8081241 | 0.79 | BDKRB1 (0.44) | AGTR1AGTR2BDKRB1LTB4R2 | |
| SCHEMBL8953441 | 0.78 | BDKRB1 (0.38) | BDKRB1 | |
| SCHEMBL9486277 | 0.76 | LTB4R2 (0.44) | AGTR1AGTR2LTB4R2 | |
| SCHEMBL9263765 | 0.75 | AGTR1 (0.45) | AGTR1AGTR2 | |
| SCHEMBL9478555 | 0.74 | AGTR1 (0.38) | AGTR1AGTR2MAPTPOLBLMNA | |
| SCHEMBL7575469 | 0.73 | BDKRB1 (0.44) | AGTR1AGTR2BDKRB1LTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5242928-A | Angiotensin II antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-09-07 | — | — | US | disclosed |