Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.30 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.30 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9140383 | 0.87 | OR51E2 (0.31) | OR51E2TP53TDP1 | |
| SCHEMBL4892112 | 0.76 | TP53 (0.35) | TP53 | |
| SCHEMBL27299236 | 0.75 | — | — | |
| SCHEMBL1403754 | 0.74 | — | — | |
| SCHEMBL589943 | 0.74 | — | — | |
| Methyl Alcohol SCHEMBL9810522 | 0.73 | TP53 (0.44) | OR51E2TP53TDP1TSHRSLC7A5 | |
| SCHEMBL4892191 | 0.73 | TP53 (0.32) | TP53TSHR | |
| SCHEMBL2553210 | 0.73 | — | — | |
| SCHEMBL41377 | 0.73 | TSHR (0.44) | OR51E2TP53TDP1TSHRCYP2C9 | |
| SCHEMBL11358490 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2677996-B1 | COMPOSITION FOR DYEING KERATINOUS FIBRES COMPRISING A DIRECT DYE HAVING A DISULPHIDE/THIOL FUNCTIONAL GROUP, A THICKENING POLYMER, AN ETHOXYLATED FATTY ALCOHOL AND/OR A NONIONIC SURFACTANT, AN ALKALINE AGENT AND A REDUCING AGENT | L'ORÉAL (FR) | 2017-11-29 | — | — | EP | claimed |
| EP-2070514-B1 | Method for long-lasting hair treatment of fibre in four steps | L'ORÉAL (FR) | 2017-04-12 | — | — | EP | claimed |
| US-20140075687-A1 | COMPOSITION FOR DYEING KERATINOUS FIBRES COMPRISING A DIRECT DYE HAVING A DISULPHIDE/THIOL FUNCTIONAL GROUP, A THICKENING POLYMER, AN ETHOXYLATED FATTY ALCOHOL AND/OR A NONIONIC SURFACTANT, AN ALKALINE AGENT AND A REDUCING AGENT | L'OREAL (FR) | 2014-03-20 | — | — | US | claimed |
| EP-1671622-B2 | Hair protein assay method | OREAL (FR) | 2013-04-10 | — | — | EP | claimed |
| WO-2012113720-A2 | COMPOSITION FOR DYEING KERATINOUS FIBRES COMPRISING A DIRECT DYE HAVING A DISULPHIDE/THIOL FUNCTIONAL GROUP, A THICKENING POLYMER, AN ETHOXYLATED FATTY ALCOHOL AND/OR A NONIONIC SURFACTANT, AN ALKALINE AGENT AND A REDUCING AGENT | L'OREAL (FR) | 2012-08-30 | — | — | WO | claimed |
| US-20100209375-A1 | PROCESS FOR TREATING KERATIN FIBERS WITH AT LEAST ONE HETEROCYCLIC DISULFIDE ENTITY IN THE PRESENCE OF AT LEAST ONE REDUCING AGENT, OPTIONALLY HEAT, AND OPTIONALLY AT ALKALINE PH. | L'OREAL S.A. (FR) | 2010-08-19 | — | — | US | claimed |
| EP-1671622-B1 | Hair protein assay method | OREAL (FR) | 2009-04-08 | — | — | EP | claimed |
| US-20060140893-A1 | Assay of hair proteins | L'OREAL (FR) | 2006-06-29 | — | — | US | claimed |
| US-5843420-A | Method for extracting malodorous compounds present in a formulation containing at least one compound carrying a thiol group and deodorized compositions thus obtained | L'OREAL (FR) | 1998-12-01 | — | — | US | claimed |
| EP-0638550-B1 | Method for extracting malodorous compounds present in a formulation containing at least one compound with a thiol group and deodorised compositions thus obtained | OREAL (FR) | 1998-01-07 | — | — | EP | claimed |
| EP-0622109-B1 | Process for deodorizing a formulation comprising at least one compound bearing a thiol group | OREAL (FR) | 1997-07-30 | — | — | EP | claimed |
| US-5531987-A | Method for extracting malodorous compounds present in a formulation containing at least one compound carrying a thiol group and deodorized compositions thus obtained | L'OREAL (FR) | 1996-07-02 | — | — | US | claimed |
| EP-2677996-B1 | COMPOSITION FOR DYEING KERATINOUS FIBRES COMPRISING A DIRECT DYE HAVING A DISULPHIDE/THIOL FUNCTIONAL GROUP, A THICKENING POLYMER, AN ETHOXYLATED FATTY ALCOHOL AND/OR A NONIONIC SURFACTANT, AN ALKALINE AGENT AND A REDUCING AGENT | L'ORÉAL (FR) | 2017-11-29 | — | — | EP | disclosed |
| US-9775419-B2 | Hair treatment method | L'OREAL (FR) | 2017-10-03 | — | — | US | disclosed |
| EP-3220886-A1 | COMPOSITION COMPRISING AN ORTHO-DIPHENOL DERIVATIVE, AN ALKALI METAL (BI)CARBONATE, A WATER-SOLUBLE ORGANIC SOLVENT AND A REDUCING AGENT | L'Oréal (FR) | 2017-09-27 | — | — | EP | disclosed |
| US-9522106-B2 | Composition for dyeing keratinous fibres comprising a direct dye having a disulphide/thiol functional group, a thickening polymer, an ethoxylated fatty alcohol and/or a nonionic surfactant, an alkaline agent and a reducing agent | L'OREAL (FR) | 2016-12-20 | — | — | US | disclosed |
| US-5655552-A | APPLYING ACIDIC COMPOSITION TO KERATINOUS MATERIAL HELD UNDER TENSION, RINSING, APPLYING THIOL REDUCING AGENT, RINSING, APPLYING OXIDIZING AGENT, RINSING, RELEASING TENSION | L'OREAL (FR) | 1997-08-12 | — | — | US | disclosed |
| US-5570708-A | Process for the permanent reshaping of keratinous material | L'OREAL (FR) | 1996-11-05 | — | — | US | disclosed |
| US-5531987-A | Method for extracting malodorous compounds present in a formulation containing at least one compound carrying a thiol group and deodorized compositions thus obtained | L'OREAL (FR) | 1996-07-02 | — | — | US | disclosed |
| US-5458848-A | Deodorizing | L'OREAL (FR) | 1995-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100209375-A1 | PROCESS FOR TREATING KERATIN FIBERS WITH AT LEAST ONE HETEROCYCLIC DISULFIDE ENTITY IN THE PRESENCE OF AT LEAST ONE REDUCING AGENT, OPTIONALLY HEAT, AND OPTIONALLY AT ALKALINE PH. | KRT18, CRYAA, CUTA | OR51E2 3424/4885TP53 1420/4885TDP1 2764/4885 |
| US-20140075687-A1 | COMPOSITION FOR DYEING KERATINOUS FIBRES COMPRISING A DIRECT DYE HAVING A DISULPHIDE/THIOL FUNCTIONAL GROUP, A THICKENING POLYMER, AN ETHOXYLATED FATTY ALCOHOL AND/OR A NONIONIC SURFACTANT, AN ALKALINE AGENT AND A REDUCING AGENT | KRT18, ESD, ADH5 | OR51E2 1175/4885TP53 3259/4885TDP1 2807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.