Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.52 |
| ▸ | MME | P08473 | 2/20 | 0.47 |
| ▸ | MMP12 | P39900 | 3/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | MMP14 | P50281 | 1/20 | 0.44 |
| ▸ | CTSG | P08311 | 1/20 | 0.42 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CPA1 | P15085 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
| ▸ | CPB1 | P15086 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8255233 | 0.82 | MMP3 (0.47) | ACEMMEMMP12MMP2MMP13 | |
| SCHEMBL5869885 | 0.82 | MMP3 (0.47) | ACEMMEMMP12MMP2MMP13 | |
| SCHEMBL4886945 | 0.77 | MMP2 (0.46) | MMEMMP12MMP2MMP9MMP13 | |
| SCHEMBL4883081 | 0.77 | MMP2 (0.46) | MMEMMP12MMP2MMP9MMP13 | |
| SCHEMBL4883091 | 0.77 | MMP2 (0.46) | MMEMMP12MMP2MMP9MMP13 | |
| SCHEMBL8257746 | 0.76 | MME (0.66) | ACEMMEMMP12MMP2MMP9 | |
| SCHEMBL5869275 | 0.76 | MME (0.66) | ACEMMEMMP12MMP2MMP9 | |
| SCHEMBL23120332 | 0.75 | SMN1; SMN2 (0.49) | ACECTSGCTRB1MEN1HTT | |
| SCHEMBL8705659 | 0.75 | GGT1 (0.50) | ACEMMEMMP2MMP9MEN1 | |
| SCHEMBL14350867 | 0.75 | SMN1; SMN2 (0.49) | ACECTSGCTRB1MEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0659193-A1 | PLATELET AGGREGATION INHIBITORS | G.D. Searle & Co. (US) | 1995-06-28 | — | — | EP | disclosed |