Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9039006 | 0.86 | SIGMAR1 (0.47) | SIGMAR1MEN1TP53CYP1A2CYP3A4 | |
| SCHEMBL6984315 | 0.84 | HTR1A (0.49) | SIGMAR1HTR7DRD2DRD4DRD3 | |
| SCHEMBL9580851 | 0.83 | KCNH2 (0.47) | CHRM2CHRM4CHRM5CHRM1DRD2 | |
| SCHEMBL9041354 | 0.83 | L3MBTL1 (0.39) | MEN1KMT2AHTR7 | |
| SCHEMBL6988196 | 0.83 | HTR1A (0.50) | SIGMAR1HTR7DRD2DRD3 | |
| SCHEMBL6991218 | 0.83 | HTR1A (0.50) | SIGMAR1HTR7DRD2DRD3 | |
| SCHEMBL6988025 | 0.82 | L3MBTL1 (0.39) | MEN1KMT2AGRM2 | |
| SCHEMBL6990381 | 0.82 | HTR1A (0.49) | SIGMAR1HTR7DRD2DRD4DRD3 | |
| SCHEMBL6989349 | 0.82 | SIGMAR1 (0.47) | SIGMAR1MEN1TP53CYP1A2CYP3A4 | |
| SCHEMBL6987269 | 0.81 | L3MBTL1 (0.38) | MEN1KMT2AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5416082-A | Antiserotonine agents | SUNTORY LIMITED (JP) | 1995-05-16 | — | — | US | disclosed |
| US-5391731-A | Useful therapeutics for circulatory diseases | SUNTORY LIMITED (JP) | 1995-02-21 | — | — | US | disclosed |
| US-5206239-A | Cardiovascular disorders | SUNTORY LIMITED (JP) | 1993-04-27 | — | — | US | disclosed |