Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 5/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9346189 | 0.84 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9320828 | 0.77 | CYP1A2 (0.56) | CYP1A2CYP2C9CYP2C19CYP3A4CYP2D6 | |
| SCHEMBL20386561 | 0.76 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL17400136 | 0.73 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9181548 | 0.72 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL24231223 | 0.72 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL14018354 | 0.72 | CALM1 (0.55) | ALDH1A1L3MBTL1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9561444 | 0.72 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9768685 | 0.72 | CALM1 (0.55) | ALDH1A1L3MBTL1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL36869 | 0.71 | ALDH1A1 (0.72) | ALDH1A1L3MBTL1CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3264593-A | — | — | None | — | — | JP | disclosed |
| EP-0446895-B1 | Novel organic silicon compound, method of its production, and photoreceptor for electrophotography incorporating it | KAO CORP (JP) | 1995-08-02 | — | — | EP | disclosed |
| US-5352554-A | Organic silicon compound, method of its production, and photoreceptor for electrophotography incorporating it | KAO CORPORATION (JP) | 1994-10-04 | — | — | US | disclosed |
| US-5187310-A | Sensitivity, durability | KAO CORPORATION (JP) | 1993-02-16 | — | — | US | disclosed |
| JP-H03264593-A | NOVEL SILYLATED TRIARYLAMINE COMPOUND AND PREPARATION THEREOF, AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR CONTAINING SAME | KAO CORP | 1991-11-25 | — | — | JP | disclosed |
| EP-0446895-A1 | Novel organic silicon compound, method of its production, and photoreceptor for electrophotography incorporating it | Kao Corporation (JP) | 1991-09-18 | — | — | EP | disclosed |