Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 4/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 3/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9182853 | 0.89 | CASP3 (0.36) | EGLN2CYP2A6RXRACASP3MALT1 | |
| SCHEMBL9180722 | 0.79 | KMT2A (0.40) | MAOBMAOA | |
| SCHEMBL9182860 | 0.78 | HPGD (0.36) | — | |
| SCHEMBL23920288 | 0.76 | CYP2A6 (0.39) | CYP2A6HTR2AHTR2CHTR2BCYP11B2 | |
| SCHEMBL9179384 | 0.75 | KDM4E (0.42) | MAOB | |
| SCHEMBL4764684 | 0.73 | SHMT2 (0.39) | CASP3IDO1MAOBMAOA | |
| SCHEMBL29141181 | 0.69 | CASP3 (0.43) | PGRCASP3MAOBMAOAMALT1 | |
| SCHEMBL30711519 | 0.69 | CASP3 (0.43) | PGRCASP3MAOBMAOAMALT1 | |
| SCHEMBL9180114 | 0.69 | CASP3 (0.39) | EGLN2CYP2A6CASP3MALT1HTR2A | |
| SCHEMBL9178830 | 0.69 | KDM4E (0.40) | HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5444071-A | Hypotensive agent | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1995-08-22 | — | — | US | disclosed |
| EP-0412848-B1 | Quinoline derivatives, process for their preparation and their use as medicaments | ICI PLC (GB) | 1995-01-18 | — | — | EP | disclosed |
| EP-0412848-A2 | Quinoline derivatives, process for their preparation and their use as medicaments | ZENECA LIMITED (GB) | 1991-02-13 | — | — | EP | disclosed |