SCHEMBL91834

SCHEMBL91834

CCCOc1cc(OCCC)c(-c2cc(F)c(S(=O)(=O)C(F)(F)F)c(F)c2)c(OCCC)c1

nearest known ligand 0.34

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GHSR Q92847 1/20 0.34
RXFP1 Q9HBX9 1/20 0.34
KAT6A Q92794 4/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
ADORA3 P0DMS8 1/20 0.32
ELANE P08246 2/20 0.32
EPAS1 Q99814 5/20 0.32
FFAR1 O14842 2/20 0.31
PTPN7 P35236 1/20 0.31
DUSP3 P51452 1/20 0.31
CYP1A1 P04798 1/20 0.30
CYP1B1 Q16678 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL91833 0.88 RXFP1 (0.33) RXFP1KAT6AELANEEPAS1FFAR1
SCHEMBL91910 0.79 ADORA3 (0.35) ADORA3ELANEFFAR1
SCHEMBL14075505 0.78 FFAR1 (0.35) ADORA3ELANEFFAR1
SCHEMBL91829 0.75 ADORA3 (0.33) ADORA3ELANEFFAR1
SCHEMBL91835 0.74 RARA (0.36) ADORA3FFAR1PTPN7DUSP3CYP1A1
SCHEMBL4415939 0.72 FFAR1 (0.32) FFAR1
SCHEMBL4422884 0.72 FFAR1 (0.32) FFAR1PTPN7DUSP3
SCHEMBL91982 0.71 RARA (0.38) ADORA3FFAR1
SCHEMBL13863856 0.71 FFAR1 (0.34) ELANEFFAR1PTPN7DUSP3CYP1A1
SCHEMBL3624809 0.70 GAA (0.43) ADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8129002-B2 Compounds for use in liquid crystal media MERCK PATENT GMBH (DE) 2012-03-06 US disclosed
US-7531106-B2 Mesogenic compounds, medium for electro-optical displays and electro-optical display MERCK PATENT GMBH (DE) 2009-05-12 US disclosed