SCHEMBL280367

SCHEMBL280367

CN1c2ccccc2C(C)(C)c2ccccc21

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 7/20 0.58
LMNA P02545 7/20 0.58
MAPT P10636 12/20 0.53
KMT2A Q03164 9/20 0.52
CYP2D6 P10635 2/20 0.52
CYP1A2 P05177 1/20 0.52
MEN1 O00255 8/20 0.50
KDM4E B2RXH2 7/20 0.50
THRB P10828 4/20 0.50
RECQL P46063 4/20 0.50
GAA P10253 4/20 0.50
ALDH1A1 P00352 4/20 0.50
TSHR P16473 2/20 0.50
NPSR1 Q6W5P4 1/20 0.50
HSD17B10 Q99714 2/20 0.49
POLB P06746 2/20 0.49
NPC1 O15118 1/20 0.49
CYP3A4 P08684 1/20 0.49
APOBEC3A P31941 1/20 0.49
CYP2C19 P33261 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29438184 1.00 HTT (0.58) HTTLMNAMAPTKMT2ACYP2D6
SCHEMBL12723265 0.91 HTT (0.51) HTTLMNAMAPTKMT2ACYP2D6
Boric Acid SCHEMBL31441081 0.91 MAPT (0.51) HTTLMNAMAPTKMT2ACYP2D6
SCHEMBL23056710 0.89 HTT (0.49) HTTLMNAMAPTKMT2ACYP2D6
SCHEMBL19846097 0.86 MAPT (0.53) HTTLMNAMAPTKMT2ACYP2D6
SCHEMBL12841615 0.86 HTT (0.47) HTTLMNAMAPTKMT2ACYP2D6
SCHEMBL10133697 0.85 LMNA (0.48) HTTLMNAMAPTKMT2ACYP2D6
SCHEMBL12793252 0.84 MAPT (0.48) HTTLMNAMAPTKMT2ACYP2D6
SCHEMBL17430596 0.83 MAPT (0.46) HTTLMNAMAPTKMT2ACYP2D6
SCHEMBL8397425 0.82 HTT (0.51) HTTLMNAMAPTKMT2ACYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 431 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024160834-A1 METHOD FOR PRODUCING A POLYMER, IN PARTICULAR FOR A MEMBRANE, POLYMER, MEMBRANE AND USE OF A MEMBRANE Forschungszentrum Jülich GmbH (DE) 2024-08-08 WO disclosed
US-12048238-B2 Organometallic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2024-07-23 US disclosed
US-20240244870-A1 LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2024-07-18 US disclosed
US-20240244952-A1 ORGANIC LIGHT-EMITTING DEVICE AND ORGANOMETALLIC COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2024-07-18 US disclosed
US-20240239754-A1 PHENANTHROIMIDAZOLE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF GUANGDONG UNIVERSITY OF TECHNOLOGY (CN) 2024-07-18 US disclosed
US-20240239754-A1 PHENANTHROIMIDAZOLE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF GUANGDONG UNIVERSITY OF TECHNOLOGY (CN) 2024-07-18 US disclosed
US-11980091-B2 Organic electroluminescence device and compound for organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2024-05-07 US disclosed
US-11980091-B2 Organic electroluminescence device and compound for organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2024-05-07 US disclosed
US-11912729-B2 Compound, display panel and display apparatus WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2024-02-27 US disclosed
US-20240032415-A1 LIGHT-EMITTING DEVICE, ELECTRONIC APPARATUS INCLUDING THE SAME, AND ORGANOMETALLIC COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2024-01-25 US disclosed
US-7811467-B2 Optical film SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-10-12 US disclosed
US-20100219406-A1 USE OF ACRIDINE DERIVATIVES AS MATRIX MATERIALS AND/OR ELECTRON BLOCKERS IN OLEDS BASF SE (DE) 2010-09-02 US disclosed
WO-2010079051-A1 SILYL AND HETEROATOM SUBSTITUTED COMPOUNDS SELECTED FROM CARBAZOLES, DIBENZOFURANS, DIBENZOTHIOPHENES AND DIBENZO PHOSPHOLES AND THE APPLICATION THEREOF IN ORGANIC ELECTRONICS BASF SE (DE) 2010-07-15 WO disclosed
WO-2010050781-A1 NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME GRACEL DISPLAY INC. (KR) 2010-05-06 WO disclosed
US-20100051106-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-03-04 US disclosed
US-20100012931-A1 POLYCYCLIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2010-01-21 US disclosed
EP-2141214-A2 Novel organic electroluminescent compounds and organic electroluminescent device using the same Gracel Display Inc. (KR) 2010-01-06 EP disclosed
US-20070298191-A1 Optical Film SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-12-27 US disclosed
US-20070298191-A1 Optical Film SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-12-27 US disclosed
US-20070155713-A1 Nitrogen-containing heterocyclic compounds and use thereof ONO PHARMACEUTICAL CO., LTD. (JP) 2007-07-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240239754-A1 PHENANTHROIMIDAZOLE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF PAH, HTR3D, CYP3A4 HTT 2545/4885LMNA 1921/4885MAPT 2223/4885
US-20240244952-A1 ORGANIC LIGHT-EMITTING DEVICE AND ORGANOMETALLIC COMPOUND LEF1, OCIAD1, OXA1L HTT 4818/4885LMNA 3213/4885MAPT 1797/4885
US-12048238-B2 Organometallic compound and organic light-emitting device including the same TRPC1, PPOX, LAGE3 HTT 1271/4885LMNA 3314/4885MAPT 1133/4885
US-20240032415-A1 LIGHT-EMITTING DEVICE, ELECTRONIC APPARATUS INCLUDING THE SAME, AND ORGANOMETALLIC COMPOUND LAGE3, CRY1, LEF1 HTT 4229/4885LMNA 3517/4885MAPT 2594/4885
US-20100051106-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same RPL36, RPL39, RPL36A HTT 4013/4885LMNA 4186/4885MAPT 3713/4885
US-11980091-B2 Organic electroluminescence device and compound for organic electroluminescence device LEF1, PIEZO1, OCIAD1 HTT 4223/4885LMNA 1139/4885MAPT 3267/4885
US-20070155713-A1 Nitrogen-containing heterocyclic compounds and use thereof NNMT, HLA-DRB1, NNT HTT 1573/4885LMNA 4575/4885MAPT 267/4885
US-20100012931-A1 POLYCYCLIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME KCNC1, EED, BMI1 HTT 2401/4885LMNA 693/4885MAPT 1303/4885
US-11912729-B2 Compound, display panel and display apparatus SAV1, TRPA1, C1S HTT 1991/4885LMNA 2079/4885MAPT 2425/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.