Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 7/20 | 0.46 |
| ▸ | HTR1A | P08908 | 4/20 | 0.44 |
| ▸ | HTR1B | P28222 | 2/20 | 0.44 |
| ▸ | HTR1D | P28221 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYBB | P04839 | 2/20 | 0.42 |
| ▸ | NOX5 | Q96PH1 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9186984 | 0.95 | NCF1 (0.49) | NCF1HTR1AHTR1BHTR1DSLC6A4 | |
| SCHEMBL2164367 | 0.94 | NCF1 (0.51) | NCF1HTR1AHTR1BHTR1DSLC6A4 | |
| SCHEMBL5211140 | 0.92 | HTR1A (0.45) | NCF1HTR1AHTR1BHTR1DSLC6A4 | |
| SCHEMBL23412188 | 0.90 | NCF1 (0.51) | NCF1HTR1AHTR1BHTR1DSLC6A4 | |
| SCHEMBL23412437 | 0.88 | NCF1 (0.58) | NCF1HTR1AHTR1BHTR1DSLC6A4 | |
| SCHEMBL23412378 | 0.88 | MAPT (0.52) | NCF1HTR1AHTR1BHTR1DSLC6A4 | |
| SCHEMBL8068790 | 0.85 | ALDH1A1 (0.48) | NCF1HTR1AHTR1BHTR1DSLC6A4 | |
| SCHEMBL8058421 | 0.83 | NCF1 (0.50) | NCF1HTR1AHTR1BHTR1DSLC6A4 | |
| SCHEMBL94707 | 0.83 | NCF1 (0.46) | NCF1HTR1AHTR1BHTR1DSLC6A4 | |
| SCHEMBL827493 | 0.83 | HTR1B (0.47) | NCF1HTR1AHTR1BHTR1DSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0658160-A1 | ANTIPSYCHOTIC QUINOLINE DERIVATIVES OF BENZODIOXANMETHYLAMINE | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-06-21 | — | — | EP | disclosed |
| US-5405843-A | Anticancer drug potentiators | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1995-04-11 | — | — | US | disclosed |
| EP-0363212-B1 | Novel heterocyclic compounds and anticancer-drug reinforcing agents containing them as effective components | MITSUI TOATSU CHEMICALS (JP) | 1995-01-04 | — | — | EP | disclosed |
| WO-1994005655-A1 | ANTIPSYCHOTIC QUINOLINE DERIVATIVES OF BENZODIOXANMETHYLAMINE | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-03-17 | — | — | WO | disclosed |
| US-5235055-A | Antipsychotic quinoline derivatives of benzodioxanmethylamine | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-08-10 | — | — | US | disclosed |
| US-5204348-A | Quinoline derivatives | MITSUI TOATSU CHEMICALS INC. (JP) | 1993-04-20 | — | — | US | disclosed |
| US-5112817-A | Anticancer Drug Potentiators | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1992-05-12 | — | — | US | disclosed |
| EP-0363212-A2 | Novel heterocyclic compounds and anticancer-drug reinforcing agents containing them as effective components | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-04-11 | — | — | EP | disclosed |