Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.43 |
| ▸ | CES1 | P23141 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.31 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13863899 | 0.85 | CES2 (0.34) | CES2CES1 | |
| SCHEMBL27486692 | 0.78 | CES2 (0.39) | CES2CES1CA1CA2CA4 | |
| SCHEMBL10027422 | 0.77 | HDAC1 (0.41) | TAAR1 | |
| SCHEMBL10448645 | 0.75 | ERN1 (0.37) | — | |
| SCHEMBL13863896 | 0.75 | ANPEP (0.38) | — | |
| SCHEMBL1998090 | 0.73 | ALDH1A1 (0.56) | CES2CES1CA1CA2CA12 | |
| SCHEMBL12152576 | 0.73 | CES2 (0.42) | CES2CES1CA1CA2CA4 | |
| SCHEMBL3759331 | 0.73 | CES2 (0.36) | CES2CES1 | |
| SCHEMBL25956250 | 0.73 | CES2 (0.36) | CES2CES1 | |
| SCHEMBL91919 | 0.73 | DAO (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11795398-B2 | Liquid-crystalline medium and liquid-crystal display comprising the same and compounds | MERCK PATENT GMBH (DE) | 2023-10-24 | — | — | US | disclosed |
| US-11788009-B2 | Liquid-crystalline medium for use in a switching element | MERCK PATENT GMBH (DE) | 2023-10-17 | — | — | US | disclosed |
| US-20230323209-A1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2023-10-12 | — | — | US | disclosed |
| US-11760931-B2 | Liquid-crystalline medium for use in a switching element | MERCK PATENT GMBH (DE) | 2023-09-19 | — | — | US | disclosed |
| US-11762241-B2 | Device for the regulation of light transmission | MERCK PATENT GMBH (DE) | 2023-09-19 | — | — | US | disclosed |
| US-11739266-B2 | Polymerisable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2023-08-29 | — | — | US | disclosed |
| US-11718791-B2 | Polymerisable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2023-08-08 | — | — | US | disclosed |
| US-11702597-B2 | Azo dye | MERCK PATENT GMBH (DE) | 2023-07-18 | — | — | US | disclosed |
| US-11685863-B2 | Polymerisable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2023-06-27 | — | — | US | disclosed |
| US-11667841-B2 | Dibenzofuran and dibenzothiophene derivatives | MERCK PATENT GMBH (DE) | 2023-06-06 | — | — | US | disclosed |
| US-7531106-B2 | Mesogenic compounds, medium for electro-optical displays and electro-optical display | MERCK PATENT GMBH (DE) | 2009-05-12 | — | — | US | disclosed |
| US-7482044-B2 | Liquid crystalline medium and liquid crystal display | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2009-01-27 | — | — | US | disclosed |
| US-7445819-B2 | Liquid crystalline medium and liquid crystal display | MERCK PATENT GMBH (DE) | 2008-11-04 | — | — | US | disclosed |
| US-7442419-B2 | Comprising one or more dielectrically positive compounds having a dielectric anisotropy of more than 3; twisted Nematic (TN) or Plane Switching (IPS) type; low rotational viscosity; polycyclo cyclohexyl fluorocarbon benzyl ether derivatives, electrooptics | MERCK PATENT GMBH (DE) | 2008-10-28 | — | — | US | disclosed |
| US-7438956-B2 | Liquid-crystalline medium and liquid-crystal display | MERCK PATENT GMBH (DE) | 2008-10-21 | — | — | US | disclosed |
| US-20080149890-A1 | Liquid Crystal Composition | ADEKA CORPORATION (JP) | 2008-06-26 | — | — | US | disclosed |
| US-20080124492-A1 | Liquid crystalline medium and liquid crystal display | MERCK PATENT GMBH | 2008-05-29 | — | — | US | disclosed |
| US-20070235688-A1 | Liquid crystalline medium and liquid crystal display | MERCK PATENT GESELLSCHAFT | 2007-10-11 | — | — | US | disclosed |
| US-20070228327-A1 | LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2007-10-04 | — | — | US | disclosed |
| US-20070176146-A1 | Liquid-crystalline medium and liquid-crystal display | MERCK PATENT GMBH (DE) | 2007-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11718791-B2 | Polymerisable compounds and the use thereof in liquid-crystal displays | VCL, ILK, LCP1 | CES2 1236/4885CES1 4288/4885CA1 1516/4885 |
| US-11685863-B2 | Polymerisable compounds and the use thereof in liquid-crystal displays | LPXN, VCL, LCP1 | CES2 2435/4885CES1 4483/4885CA1 626/4885 |
| US-11667841-B2 | Dibenzofuran and dibenzothiophene derivatives | DDT, MYT1, DBF4 | CES2 2222/4885CES1 2892/4885CA1 591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.