Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 2/20 | 0.49 |
| ▸ | GABRD | O14764 | 2/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.49 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.49 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.49 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.49 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.49 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.49 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.49 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.49 |
| ▸ | GABRE | P78334 | 2/20 | 0.49 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.49 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.49 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.49 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9185559 | 0.84 | TTR (0.59) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL17820661 | 0.84 | GABRP (0.49) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL11385812 | 0.83 | MAOA (0.63) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9189119 | 0.81 | KDM1A (0.61) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6524056 | 0.80 | MAPT (0.69) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9187037 | 0.79 | KDM1A (0.53) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL17819869 | 0.76 | GABRP (0.46) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL11661116 | 0.76 | ALDH1A1 (0.51) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8711628 | 0.76 | MAOA (0.64) | MEN1MAPTKMT2A | |
| SCHEMBL11233028 | 0.76 | KDM1A (0.53) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5176854-A | Xanthone Derivatives | HITACHI, LTD. (JP) | 1993-01-05 | — | — | US | claimed |
| EP-0315140-B1 | Non-linear optical device | HITACHI LTD (JP) | 1995-08-23 | — | — | EP | disclosed |
| US-5176854-A | Xanthone Derivatives | HITACHI, LTD. (JP) | 1993-01-05 | — | — | US | disclosed |
| EP-0315140-A2 | Non-linear optical device | HITACHI, LTD. (JP) | 1989-05-10 | — | — | EP | disclosed |