Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 3/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL133412 | 0.88 | HSD17B1 (0.45) | HSD17B1HSD17B2PARP1LMNAHPGD | |
| SCHEMBL9853340 | 0.86 | DHODH (0.45) | HSD17B1HSD17B2PARP1HPGDALDH1A1 | |
| SCHEMBL147931 | 0.83 | ACHE (0.52) | HSD17B1HSD17B2LMNAALDH1A1MAPT | |
| SCHEMBL29391727 | 0.83 | ACHE (0.52) | HSD17B1HSD17B2LMNAALDH1A1MAPT | |
| SCHEMBL28654162 | 0.82 | POLB (0.49) | HSD17B1HSD17B2PARP1HPGDTDP1 | |
| SCHEMBL8766625 | 0.81 | ACHE (0.50) | HSD17B1HSD17B2LMNAALDH1A1MAPT | |
| SCHEMBL134721 | 0.81 | ACHE (0.55) | HSD17B1HSD17B2LMNAALDH1A1MAPT | |
| SCHEMBL29692933 | 0.81 | ACHE (0.55) | HSD17B1HSD17B2LMNAALDH1A1MAPT | |
| SCHEMBL13351679 | 0.81 | HSD17B1 (0.39) | HSD17B1HSD17B2PARP1LMNAHPGD | |
| SCHEMBL22910885 | 0.80 | HSD17B1 (0.46) | HSD17B1HSD17B2PARP1LMNAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0455247-B1 | m-Phenylenediamine compound and electrophotosensitive material using said compound | MITA INDUSTRIAL CO LTD (JP) | 1995-09-13 | — | — | EP | disclosed |
| EP-0455247-A2 | m-Phenylenediamine compound and electrophotosensitive material using said compound | MITA INDUSTRIAL CO. LTD. (JP) | 1991-11-06 | — | — | EP | disclosed |