Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.45 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.44 |
| ▸ | TPMT | P51580 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL133412 | 0.88 | HSD17B1 (0.45) | HSD17B1HSD17B2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9188288 | 0.86 | HSD17B1 (0.44) | HSD17B1HSD17B2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL3739645 | 0.84 | HSD17B1 (0.50) | DHODHHSD17B1HSD17B2CYP3A4CYP2C9 | |
| SCHEMBL15240684 | 0.84 | HSD17B1 (0.50) | DHODHHSD17B1HSD17B2CYP3A4CYP2C9 | |
| SCHEMBL147931 | 0.83 | ACHE (0.52) | HSD17B1HSD17B2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL29391727 | 0.83 | ACHE (0.52) | HSD17B1HSD17B2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL28654162 | 0.82 | POLB (0.49) | HSD17B1HSD17B2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7899657 | 0.82 | HSD17B1 (0.55) | DHODHHSD17B1HSD17B2POLBALDH1A1 | |
| SCHEMBL14342109 | 0.81 | ACHE (0.46) | CYP3A4CYP2C9CYP2C19ALDH1A1NPC1 | |
| SCHEMBL21918074 | 0.81 | ACHE (0.46) | CYP3A4CYP2C9CYP2C19ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0455247-A2 | m-Phenylenediamine compound and electrophotosensitive material using said compound | MITA INDUSTRIAL CO. LTD. (JP) | 1991-11-06 | — | — | EP | disclosed |