Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.43 |
| ▸ | MAOA | P21397 | 3/20 | 0.39 |
| ▸ | MMP1 | P03956 | 5/20 | 0.37 |
| ▸ | MMP2 | P08253 | 5/20 | 0.37 |
| ▸ | MMP9 | P14780 | 5/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9194181 | 0.87 | MEN1 (0.34) | MAOBMAOAMEN1NPC1LMNA | |
| SCHEMBL9190865 | 0.86 | MMP1 (0.40) | MAOBMMP1MMP2MMP9EGFR | |
| SCHEMBL9253964 | 0.85 | MMP1 (0.41) | MMP1MMP2MMP9EGFRMEN1 | |
| SCHEMBL9191180 | 0.84 | NPC1 (0.34) | MAOBMAOAMMP1MMP2MMP9 | |
| SCHEMBL9194378 | 0.83 | EGFR (0.33) | MAOBEGFR | |
| SCHEMBL9190928 | 0.83 | AKR1C3 (0.33) | — | |
| SCHEMBL8846207 | 0.83 | AKR1C3 (0.33) | — | |
| SCHEMBL9566168 | 0.80 | FAAH (0.39) | MAOBEGFR | |
| SCHEMBL9566090 | 0.79 | RAB9A (0.47) | MEN1NPC1LMNAMAPTKMT2A | |
| SCHEMBL9192049 | 0.79 | RAB9A (0.48) | MEN1NPC1LMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5459149-A | Penta-2,4-dienamides and use as pesticides | ROUSSEL UCLAF (FR) | 1995-10-17 | — | — | US | disclosed |
| EP-0524041-B1 | Pesticides | ROUSSEL UCLAF (FR) | 1995-09-20 | — | — | EP | disclosed |
| US-5270343-A | Penta-2,4-dienamides and use as pesticides | ROUSSEL UCLAF (FR) | 1993-12-14 | — | — | US | disclosed |
| EP-0524041-A2 | Pesticides | ROUSSEL UCLAF (FR) | 1993-01-20 | — | — | EP | disclosed |