Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 9/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9192773 | 0.82 | ALDH1A1 (0.43) | KDM4EALDH1A1GAAL3MBTL1CTDSP1 | |
| SCHEMBL9196786 | 0.81 | HCAR2 (0.36) | KDM4EALDH1A1GAAAKR1B1 | |
| SCHEMBL9196608 | 0.79 | AKR1B1 (0.40) | KDM4EGAAAKR1B1MEN1KMT2A | |
| SCHEMBL9191955 | 0.72 | HCAR2 (0.45) | KDM4EALDH1A1HSD17B10MEN1TSHR | |
| SCHEMBL9732171 | 0.69 | MEN1 (0.40) | KDM4EGAAL3MBTL1MEN1TSHR | |
| SCHEMBL9196781 | 0.69 | KDM4E (0.37) | KDM4EGAAAKR1B1 | |
| SCHEMBL9190029 | 0.67 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL2180069 | 0.66 | RAB9A (0.63) | KDM4EALDH1A1TDP1MEN1TSHR | |
| SCHEMBL9386679 | 0.65 | ALDH1A1 (0.44) | KDM4EALDH1A1GAAL3MBTL1CTDSP1 | |
| SCHEMBL9556162 | 0.63 | KDM4E (0.51) | KDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399856-B1 | Pteridin-4 (3H)-ones, processes for their preparation and medicaments containing them | LIPHA (FR) | 1995-08-09 | — | — | EP | disclosed |
| US-5270465-A | 4(3H)-pteridinone compounds | LIPHA, LYONNAISE INDUSTRILLE PHARMACEUTIQUE (FR) | 1993-12-14 | — | — | US | disclosed |
| US-5167949-A | Antiallergic | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1992-12-01 | — | — | US | disclosed |
| EP-0399856-A1 | Pteridin-4 (3H)-ones, processes for their preparation and medicaments containing them | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1990-11-28 | — | — | EP | disclosed |