Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 11/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9194837 | 0.80 | CDC7 (0.38) | AKR1B1KDM4EGAAHCAR2 | |
| SCHEMBL9190090 | 0.79 | KDM4E (0.40) | AKR1B1KDM4EGAAMEN1KMT2A | |
| SCHEMBL24629160 | 0.73 | ALDH1A1 (0.52) | KDM4EGAAHCAR2MEN1KMT2A | |
| SCHEMBL25903530 | 0.71 | NOS1 (0.47) | AKR1B1KDM4EGAAHCAR2MEN1 | |
| SCHEMBL9196781 | 0.70 | KDM4E (0.37) | AKR1B1KDM4EGAA | |
| SCHEMBL25899166 | 0.70 | HSD17B10 (0.49) | AKR1B1KDM4EHCAR2MEN1KMT2A | |
| SCHEMBL21403508 | 0.69 | HCAR2 (0.36) | KDM4EHCAR2MEN1KMT2ARPS6KA3 | |
| SCHEMBL5443522 | 0.66 | RPS6KA3 (0.60) | AKR1B1KDM4EGAAMEN1KMT2A | |
| SCHEMBL26887312 | 0.62 | DAO (0.38) | KDM4EGAAHCAR2MEN1KMT2A | |
| SCHEMBL9190029 | 0.61 | ALDH1A1 (0.43) | HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399856-B1 | Pteridin-4 (3H)-ones, processes for their preparation and medicaments containing them | LIPHA (FR) | 1995-08-09 | — | — | EP | disclosed |
| US-5270465-A | 4(3H)-pteridinone compounds | LIPHA, LYONNAISE INDUSTRILLE PHARMACEUTIQUE (FR) | 1993-12-14 | — | — | US | disclosed |
| US-5167949-A | Antiallergic | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1992-12-01 | — | — | US | disclosed |
| EP-0399856-A1 | Pteridin-4 (3H)-ones, processes for their preparation and medicaments containing them | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1990-11-28 | — | — | EP | disclosed |