Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 13/20 | 0.50 |
| ▸ | RARB | P10826 | 12/20 | 0.50 |
| ▸ | RARG | P13631 | 11/20 | 0.50 |
| ▸ | RXRA | P19793 | 4/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | GNRHR | P30968 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7565094 | 0.85 | RARB (0.62) | RARARARBRARGRXRAABCB1 | |
| SCHEMBL9190381 | 0.80 | RARA (0.53) | RARARARBRARGRXRAABCB1 | |
| SCHEMBL7877006 | 0.73 | RARB (0.64) | RARARARBRARGRXRAPDK2 | |
| SCHEMBL23558363 | 0.72 | PBRM1 (0.40) | PDK2 | |
| SCHEMBL7794229 | 0.72 | RARB (0.75) | RARARARBRARGRXRAABCB1 | |
| SCHEMBL8557384 | 0.72 | RARB (0.55) | RARARARBRARGRXRAPDK2 | |
| SCHEMBL7647113 | 0.71 | ABCB1 (0.69) | RARARARBRARGRXRAABCB1 | |
| SCHEMBL7565236 | 0.71 | CD274 (0.51) | RARARARBRARGRXRAPDK2 | |
| SCHEMBL23558190 | 0.71 | HDAC6 (0.39) | PDK2 | |
| SCHEMBL23558186 | 0.71 | CYP11B2 (0.41) | PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5475017-A | Skin disorders, antitumor agents; side effect reduction | BASF AKTIENGESELLSCHAFT (DE) | 1995-12-12 | — | — | US | disclosed |
| EP-0382077-B1 | Diaryl-substituted heterocyclic compound, its preparation and medicaments and cosmetics made thereof | BASF AG (DE) | 1995-05-17 | — | — | EP | disclosed |
| US-5338749-A | Treating rheumatic or arthritic disorders | BASF AKTIENGESELLSCHAFT (DE) | 1994-08-16 | — | — | US | disclosed |
| US-5206242-A | Skin disorders | BASF AKTIENGESELLSCHAFT (DE) | 1993-04-27 | — | — | US | disclosed |
| US-5196532-A | Treatment of skin disorders | BASF AKTIENGESELLSCHAFT (DE) | 1993-03-23 | — | — | US | disclosed |
| US-5061705-A | Skin disorders | BASF AKTIENGESELLSCHAFT (DE) | 1991-10-29 | — | — | US | disclosed |
| EP-0382077-A2 | Diaryl-substituted heterocyclic compound, its preparation and medicaments and cosmetics made thereof | BASF Aktiengesellschaft (DE) | 1990-08-16 | — | — | EP | disclosed |