Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 13/20 | 0.55 |
| ▸ | RARG | P13631 | 12/20 | 0.55 |
| ▸ | RXRA | P19793 | 3/20 | 0.55 |
| ▸ | DPP4 | P27487 | 2/20 | 0.47 |
| ▸ | RARA | P10276 | 13/20 | 0.45 |
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7565094 | 0.85 | RARB (0.62) | RARBRARGRXRARARAHSD17B3 | |
| SCHEMBL7794229 | 0.79 | RARB (0.75) | RARBRARGRXRARARA | |
| SCHEMBL24794240 | 0.76 | RARG (0.58) | RARBRARGRXRARARAPDK2 | |
| SCHEMBL7793710 | 0.76 | RARB (0.62) | RARBRARGRXRARARA | |
| SCHEMBL24807991 | 0.76 | RARB (0.58) | RARBRARGRXRARARA | |
| SCHEMBL7877006 | 0.75 | RARB (0.64) | RARBRARGRXRARARAPDK2 | |
| SCHEMBL8557385 | 0.74 | RARA (0.54) | RARBRARGRXRARARA | |
| SCHEMBL7789708 | 0.74 | RARG (0.59) | RARBRARGRXRARARAPDK2 | |
| SCHEMBL5045191 | 0.74 | DPP4 (0.57) | DPP4NOS3NOS1NOS2HSD17B3 | |
| SCHEMBL4965729 | 0.73 | RARB (0.69) | RARBRARGRXRARARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5709867-A | TREATMENT OF DERMATOLOGICAL, RHEUMATIC, RESPIRATORY, CARDIOVASCULAR, AND OPHTHALMOLOGICAL DISORDERS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1998-01-20 | — | — | US | disclosed |