SCHEMBL9190993

SCHEMBL9190993

CCC(C)C(=O)c1ccc(-c2ccc(OC)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.49
NPC1 O15118 1/20 0.49
RAB9A P51151 1/20 0.49
CYP1A2 P05177 1/20 0.49
CES2 O00748 1/20 0.48
CES1 P23141 1/20 0.48
CA1 P00915 4/20 0.47
CA2 P00918 4/20 0.47
KDM4E B2RXH2 1/20 0.47
HPGD P15428 1/20 0.47
MAPK1 P28482 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
HSD17B10 Q99714 1/20 0.47
SLC6A2 P23975 1/20 0.47
SLC6A4 P31645 1/20 0.47
SLC6A3 Q01959 1/20 0.47
GSK3B P49841 1/20 0.46
HDAC3 O15379 1/20 0.46
HDAC4 P56524 1/20 0.46
HDAC1 Q13547 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9405579 1.00 ALDH1A1 (0.49) ALDH1A1NPC1RAB9ACYP1A2CES2
SCHEMBL8293343 0.95 CES2 (0.53) ALDH1A1CYP1A2CES2CES1CA1
SCHEMBL21165790 0.90 PARP10 (0.54) ALDH1A1CYP1A2CES2CES1CA1
SCHEMBL678080 0.82 CES2 (0.55) ALDH1A1NPC1RAB9ACYP1A2CES2
SCHEMBL9405700 0.82 RARB (0.49) NPC1RAB9ASLC6A2SLC6A4SLC6A3
SCHEMBL9405697 0.82 RARB (0.49) NPC1RAB9ASLC6A2SLC6A4SLC6A3
SCHEMBL24221611 0.82 LMNA (0.48) ALDH1A1RAB9AKDM4EHSD17B10HDAC3
SCHEMBL28718619 0.81 SLC6A2 (0.58) ALDH1A1CYP1A2CES2CES1CA1
SCHEMBL2423154 0.81 CES2 (0.53) ALDH1A1CYP1A2CES2CES1CA1
SCHEMBL9405584 0.81 PDPK1 (0.56) ALDH1A1RAB9ACYP1A2CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0558157-B1 Naphthalene compounds MITSUBISHI GAS CHEMICAL CO (JP) 1995-11-29 EP disclosed
EP-0402110-B1 Optical active compounds and liquid crystal compositions containing such compounds WAKO PURE CHEM IND LTD (JP) 1994-12-14 EP disclosed
EP-0390322-B1 Naphthalene compounds MITSUBISHI GAS CHEMICAL CO (JP) 1994-04-27 EP disclosed
EP-0315193-B1 Optically active compound and chiral liquid crystal composition containing the same NIPPON TELEGRAPH & TELEPHONE (JP) 1994-04-06 EP disclosed
EP-0558157-A1 Naphthalene compounds MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1993-09-01 EP disclosed
US-5151549-A NAPHTHALENE COMPOUNDS MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1992-09-29 US disclosed
US-5146025-A NAPHTHALENE COMPOUNDS MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1992-09-08 US disclosed
US-5128062-A OPTICALLY ACTIVE COMPOUNDS AND LIQUID CRYSTAL COMPOSITIONS CONTAINING SUCH COMPOUNDS WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1992-07-07 US disclosed
US-5059345-A Spontaneous polarization in wide temperature range and high speed response NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1991-10-22 US disclosed
EP-0402110-A1 Optical active compounds and liquid crystal compositions containing such compounds WAKO PURE CHEMICAL INDUSTRIES LTD (JP) 1990-12-12 EP disclosed
EP-0390322-A2 Naphthalene compounds MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1990-10-03 EP disclosed
US-4913839-A USABLE AT ROOM TEMPERATURE; FAST RESPONSE SPEED; DISPLAYING MOTION PICTURES; SUITABLE FOR LARGE OR CURVED SCREENS IDEMITSU KOSAN CO., LTD. (JP) 1990-04-03 US disclosed
US-4844835-A FAST RESPONSE, DISPLAYING MOTION PICTURES IDENITSU KOSAN CO., LTD. (JP) 1989-07-04 US disclosed
EP-0315193-A2 Optically active compound and chiral liquid crystal composition containing the same NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1989-05-10 EP disclosed
EP-0228703-A2 Ferroelectric liquid crystal polymer IDEMITSU KOSAN COMPANY LIMITED (JP) 1987-07-15 EP disclosed
US-4676925-A Liquid crystalline biphenyl derivatives and mixtures thereof CHISSO CORPORATION (JP) 1987-06-30 US disclosed
EP-0131373-B1 LIQUID CRYSTALLINE BIPHENYL DERIVATIVES AND MIXTURES THEREOF Chisso Corporation (JP) 1986-12-30 EP disclosed
EP-0131373-A1 Liquid crystalline biphenyl derivatives and mixtures thereof Chisso Corporation (JP) 1985-01-16 EP disclosed