Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9194620 | 0.90 | ATF1 (0.36) | — | |
| SCHEMBL9196255 | 0.84 | PGK1 (0.34) | ALDH1A1HTTALOX15TSHR | |
| SCHEMBL9188793 | 0.81 | ALDH1A1 (0.33) | ALDH1A1HTTALOX15TSHR | |
| SCHEMBL7935910 | 0.80 | HSP90AA1 (0.35) | ALDH1A1 | |
| SCHEMBL7934055 | 0.77 | IDH2 (0.34) | ALDH1A1 | |
| SCHEMBL7807011 | 0.74 | ATF1 (0.34) | — | |
| SCHEMBL9192620 | 0.74 | KDM4E (0.35) | ALDH1A1HTT | |
| SCHEMBL7934010 | 0.74 | KMT2A (0.49) | ALDH1A1 | |
| SCHEMBL7804829 | 0.72 | NPC1 (0.44) | ALDH1A1 | |
| SCHEMBL7804843 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445644-B1 | Trifluoro- respectively chlorodifluoromethoxy pyrimidines and process for their preparation | BASF AG (DE) | 1995-05-24 | — | — | EP | disclosed |
| US-5237063-A | TRIFLUORO- AND CHLORODIFLUOROMETHOXYPYRIMIDINES AND THE PREPARATION THEREOF | BASF AKTIENGESELLSCHAFT (DE) | 1993-08-17 | — | — | US | disclosed |
| EP-0445644-A1 | Trifluoro- respectively chlorodifluoromethoxy pyrimidines and process for their preparation | BASF Aktiengesellschaft (DE) | 1991-09-11 | — | — | EP | disclosed |