Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 13/20 | 0.42 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | XDH | P47989 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9196894 | 0.91 | HCAR2 (0.38) | HCAR2HPGDALDH1A1XDHKDM4E | |
| SCHEMBL9191469 | 0.91 | HCAR2 (0.47) | HCAR2PDE5AHPGDALDH1A1KDM4E | |
| SCHEMBL9191397 | 0.86 | ALDH1A1 (0.39) | HCAR2HPGDALDH1A1XDHKDM4E | |
| SCHEMBL6440045 | 0.82 | HCAR2 (0.43) | HCAR2ALDH1A1GAAHTTRAB9A | |
| SCHEMBL9194269 | 0.81 | HCAR2 (0.33) | HCAR2HPGDALDH1A1XDHKDM4E | |
| SCHEMBL9194911 | 0.80 | RAB9A (0.51) | HCAR2HPGDALDH1A1XDHKDM4E | |
| SCHEMBL9194026 | 0.77 | HCAR2 (0.44) | HCAR2ALDH1A1GAARAB9A | |
| SCHEMBL9190029 | 0.76 | ALDH1A1 (0.43) | HCAR2ALDH1A1 | |
| SCHEMBL3817859 | 0.74 | TNKS2 (0.44) | HCAR2HPGDALDH1A1 | |
| SCHEMBL1900052 | 0.73 | ALDH1A1 (0.54) | HPGDALDH1A1XDHKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399856-B1 | Pteridin-4 (3H)-ones, processes for their preparation and medicaments containing them | LIPHA (FR) | 1995-08-09 | — | — | EP | claimed |