SCHEMBL9192103

SCHEMBL9192103

CS(=O)(=O)c1cc(C(=O)N=C(N)N)ccc1SC1CCCCC1

nearest known ligand 0.66

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SLC9A1 P19634 5/20 0.57
SLC9A2 Q9UBY0 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7800587 0.83 SLC9A1 (0.61) SLC9A1
SCHEMBL7802743 0.81 SLC9A1 (0.62) SLC9A1
SCHEMBL9436726 0.80 HPGD (0.62)
SCHEMBL9192097 0.80 CA2 (0.42)
SCHEMBL7801760 0.79 SLC9A1 (0.46) SLC9A1
Hydrochloric Acid SCHEMBL8899664 0.79 SLC9A1 (0.72) SLC9A1SLC9A2
SCHEMBL9191877 0.79 SLC9A1 (0.59) SLC9A1SLC9A2
Hydrochloric Acid SCHEMBL8816052 0.78 SLC9A1 (0.58) SLC9A1SLC9A2
SCHEMBL7798667 0.77 SLC9A1 (0.47) SLC9A1
Hydrochloric Acid SCHEMBL8896327 0.77 SLC9A1 (0.73) SLC9A1SLC9A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0416499-B1 Benzoylguanidines, process for their preparation, their use as medicaments as well as medicament containing them HOECHST AG (DE) 1995-04-26 EP disclosed
US-5292755-A USPA benzolyguanidines HOECHST AKTIENGESELLSCHAFT (DE) 1994-03-08 US disclosed
US-5091394-A BENZOYLGUANIDINES, A PROCESS FOR THEIR PREPARATION, THEIR USE AS MEDICAMENTS AND MEDICAMENTS CONTAINING THEM HOECHST AKTIENGESELLSCHAFT (DE) 1992-02-25 US disclosed
EP-0416499-A2 Benzoylguanidines, process for their preparation, their use as medicaments as well as medicament containing them HOECHST AKTIENGESELLSCHAFT (DE) 1991-03-13 EP disclosed