Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA4 | P22748 | 3/20 | 0.41 |
| ▸ | CA6 | P23280 | 3/20 | 0.41 |
| ▸ | CA7 | P43166 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9192097 | 0.80 | CA2 (0.42) | HPGDALDH1A1SMN1; SMN2NPSR1CA2 | |
| SCHEMBL9192103 | 0.80 | SLC9A1 (0.57) | — | |
| SCHEMBL8896076 | 0.78 | VCAM1 (0.48) | HPGDVCAM1ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL8896458 | 0.76 | VCAM1 (0.49) | VCAM1ALDH1A1L3MBTL1SMN1; SMN2ATM | |
| SCHEMBL507527 | 0.74 | HPGD (0.56) | HPGDALDH1A1SMN1; SMN2ATMNPSR1 | |
| SCHEMBL8894967 | 0.73 | VCAM1 (0.51) | HPGDVCAM1ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL8895236 | 0.73 | VCAM1 (0.43) | HPGDVCAM1ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL8915861 | 0.73 | PDE4A (0.44) | HPGDVCAM1ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL24495374 | 0.73 | CA2 (0.58) | HPGDCA2KMT2ACA12CA1 | |
| SCHEMBL29831649 | 0.73 | CA2 (0.58) | HPGDCA2KMT2ACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292755-A | USPA benzolyguanidines | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-03-08 | — | — | US | disclosed |
| US-5091394-A | BENZOYLGUANIDINES, A PROCESS FOR THEIR PREPARATION, THEIR USE AS MEDICAMENTS AND MEDICAMENTS CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-02-25 | — | — | US | disclosed |