Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL783319 | 0.84 | CYP1A2 (0.52) | KMT2AMEN1MAPTCYP2C9CYP2C19 | |
| SCHEMBL9192170 | 0.79 | BCHE (0.47) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL9196684 | 0.79 | MAPT (0.44) | KMT2ATDP1L3MBTL1ATMMEN1 | |
| SCHEMBL9191911 | 0.79 | LMNA (0.50) | KMT2ATDP1MEN1ALDH1A1MAPT | |
| SCHEMBL9192944 | 0.79 | KMT2A (0.55) | KMT2ATDP1L3MBTL1ATMMEN1 | |
| SCHEMBL2678410 | 0.78 | SMN1; SMN2 (0.51) | KMT2AMEN1RAB9AALDH1A1MAPT | |
| SCHEMBL1735252 | 0.74 | ADORA2A (0.51) | L3MBTL1F2RAB9AALDH1A1MAPT | |
| SCHEMBL8540787 | 0.74 | KMT2A (0.63) | KMT2AALDH1A1RXFP1CHRNB4CHRNA3 | |
| SCHEMBL9192927 | 0.74 | ATM (0.52) | KMT2ATDP1L3MBTL1ATMMEN1 | |
| SCHEMBL4599121 | 0.74 | ALDH1A1 (0.65) | KMT2AL3MBTL1MEN1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443474-B1 | 1-Phenoxycarbonyl-2-pyrrolidinone derivatives and nootropic agents | NISSHIN FLOUR MILLING CO (JP) | 1995-08-16 | — | — | EP | disclosed |
| US-5227395-A | ANTI-PLATELET AGGREGATING AGENT | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1993-07-13 | — | — | US | disclosed |
| US-5140041-A | Cognition activators, for treatment of Alzheimer's disease | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1992-08-18 | — | — | US | disclosed |
| EP-0443474-A2 | 1-Phenoxycarbonyl-2-pyrrolidinone derivatives and nootropic agents | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1991-08-28 | — | — | EP | disclosed |