Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.44 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.44 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830399 | 0.88 | PRMT1 (0.59) | PRMT1EPHX1NAAAADRA1AMAPK1 | |
| SCHEMBL9831902 | 0.85 | NAAA (0.60) | PRMT1EPHX1NAAAADRA1AMAPK1 | |
| SCHEMBL9830181 | 0.85 | NAAA (0.65) | PRMT1EPHX1NAAAADRA1AMAPK1 | |
| SCHEMBL5655426 | 0.83 | NAAA (0.68) | PRMT1EPHX1NAAAADRA1AMAPK1 | |
| SCHEMBL7897834 | 0.83 | NAAA (0.68) | PRMT1EPHX1NAAAADRA1AMAPK1 | |
| SCHEMBL9831292 | 0.83 | NAAA (0.62) | PRMT1EPHX1NAAAADRA1AMAPK1 | |
| SCHEMBL9829575 | 0.81 | NAAA (0.65) | PRMT1EPHX1NAAAADRA1AGNAI3 | |
| SCHEMBL2331473 | 0.81 | EPHX2 (0.51) | PRMT1EPHX1NAAAADRA1AGNAI3 | |
| SCHEMBL13618531 | 0.81 | ADRA1A (0.51) | PRMT1EPHX1NAAAADRA1AMAPK1 | |
| SCHEMBL5902012 | 0.78 | NAAA (0.59) | PRMT1EPHX1NAAAGNAI3GNAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585310-A4 | CROSSTALK INHIBITORS AND THEIR USES. | BIOSITE DIAGNOSTICS INC (US) | 1995-06-14 | — | — | EP | disclosed |
| EP-0585310-A1 | CROSSTALK INHIBITORS AND THEIR USES | BIOSITE DIAGNOSTICS INC. (US) | 1994-03-09 | — | — | EP | disclosed |