Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | EGFR | P00533 | 3/20 | 0.42 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CCNK | O75909 | 2/20 | 0.38 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | MMP9 | P14780 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17507869 | 0.80 | GAA (0.44) | ALDH1A1KDM4ESMN1; SMN2LMNAHTT | |
| SCHEMBL31286041 | 0.79 | RECQL (0.50) | ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL774432 | 0.78 | ALDH1A1 (0.65) | TGM2ALDH1A1KDM4ESMN1; SMN2NPSR1 | |
| SCHEMBL732581 | 0.76 | TGM2 (0.61) | TGM2ALDH1A1EGFRBTKKDM4E | |
| SCHEMBL19049396 | 0.76 | POLB (0.42) | ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL26128334 | 0.76 | TGM2 (0.60) | TGM2MMP1MMP2MMP9 | |
| SCHEMBL31201195 | 0.76 | TGM2 (0.60) | TGM2MMP1MMP2MMP9 | |
| SCHEMBL732934 | 0.75 | TGM2 (0.81) | TGM2ALDH1A1LMNATSHRMAPK1 | |
| SCHEMBL26181255 | 0.75 | TGM2 (0.63) | TGM2ALDH1A1EGFRBTKLMNA | |
| SCHEMBL1119154 | 0.74 | MMP1 (0.55) | TGM2ALDH1A1EGFRBTKKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0435634-B1 | Conductive and blocking layers for electrophotographic imaging members | XEROX CORP (US) | 1995-11-02 | — | — | EP | disclosed |
| EP-0435634-A2 | Conductive and blocking layers for electrophotographic imaging members | XEROX CORPORATION (US) | 1991-07-03 | — | — | EP | disclosed |
| US-4988597-A | MULTILAYER ELECTROGRAPHY IMAGING PROCESS AND ELEMENT, A PHOTOCONDUCTIVE LAYER, AN ELECTROCONDUCTIVE LAYER OF A PARTIALLY CRO SSLINKED POLYMER OF ACRYLAMIDOGLYCOLATE ALKYL ETHER | XEROX CORPORATION (US) | 1991-01-29 | — | — | US | disclosed |