SCHEMBL9195192

SCHEMBL9195192

CCCCN=C(C)C(CCCC)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.44
MAPK1 P28482 1/20 0.44
DDAH1 O94760 3/20 0.42
NOS1 P29475 6/20 0.41
NOS2 P35228 5/20 0.41
NOS3 P29474 3/20 0.41
MEN1 O00255 1/20 0.41
CYP2C19 P33261 1/20 0.41
KMT2A Q03164 1/20 0.41
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
TSHR P16473 1/20 0.40
BLM P54132 1/20 0.39
GPR84 Q9NQS5 3/20 0.38
FFAR1 O14842 1/20 0.38
SLC1A3 P43003 1/20 0.38
SLC1A2 P43004 1/20 0.38
SLC1A1 P43005 1/20 0.38
MAPT P10636 1/20 0.37
LCK P06239 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9195187 1.00 CA2 (0.44) CA2MAPK1DDAH1NOS1NOS2
SCHEMBL9199299 0.94 CA2 (0.42) CA2MAPK1DDAH1NOS1NOS2
SCHEMBL9199303 0.94 CA2 (0.42) CA2MAPK1DDAH1NOS1NOS2
SCHEMBL9199251 0.94 GPR84 (0.46) DDAH1NOS1NOS2NOS3MEN1
SCHEMBL9199256 0.94 GPR84 (0.46) DDAH1NOS1NOS2NOS3MEN1
SCHEMBL9196419 0.93 GPR84 (0.44) CA2MAPK1DDAH1NOS1NOS2
SCHEMBL9196426 0.93 GPR84 (0.44) CA2MAPK1DDAH1NOS1NOS2
SCHEMBL9200784 0.92 DDAH1 (0.42) CA2MAPK1DDAH1NOS1NOS2
SCHEMBL9200780 0.92 DDAH1 (0.42) CA2MAPK1DDAH1NOS1NOS2
SCHEMBL9196061 0.91 NOS2 (0.46) DDAH1NOS1NOS2NOS3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0503634-B1 Novel terpene derivatives and process for preparing the same EISAI CO LTD (JP) 1995-12-27 EP claimed