Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 5/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 3/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9477211 | 0.86 | FFAR1 (0.58) | FFAR1ALOX5ERN1FFAR4 | |
| SCHEMBL9299899 | 0.81 | ALOX5 (0.39) | FFAR1ALOX5PTGS1PTGS2GRM5 | |
| SCHEMBL9192556 | 0.78 | ALOX5 (0.45) | FFAR1ALOX5PTGS1PTGS2GRM5 | |
| SCHEMBL9195264 | 0.75 | FFAR1 (0.47) | FFAR1ALOX5ERN1 | |
| SCHEMBL9195674 | 0.74 | ALOX5 (0.47) | FFAR1ALOX5PTGS1PTGS2ALDH1A1 | |
| SCHEMBL1550725 | 0.73 | FFAR1 (1.00) | FFAR1FFAR4 | |
| SCHEMBL9192422 | 0.73 | FFAR1 (0.58) | FFAR1ALOX5PTGS1PTGS2GRM5 | |
| SCHEMBL1550227 | 0.73 | FFAR1 (0.73) | FFAR1ERN1FFAR4 | |
| SCHEMBL11036116 | 0.72 | FFAR1 (0.56) | FFAR1ERN1ALDH1A1NPSR1 | |
| SCHEMBL9192563 | 0.71 | PTGES (0.56) | ALOX5PTGS1PTGS2PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468281-B1 | Substituted phenylacetylenes, pharmaceuticals containing them and methods for the preparation of these compounds and pharmaceuticals | GRUENENTHAL GMBH (DE) | 1995-03-08 | — | — | EP | disclosed |
| US-5202349-A | Lipoxygenase inhibitors, antiasthatics | GRUENENTHAL GMBH (DE) | 1993-04-13 | — | — | US | disclosed |
| EP-0468281-A1 | Substituted phenylacetylenes, pharmaceuticals containing them and methods for the preparation of these compounds and pharmaceuticals | Grünenthal GmbH (DE) | 1992-01-29 | — | — | EP | disclosed |