Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9195772 | 0.91 | EPHX1 (0.38) | TDP1EPHX1TAS2R14ALDH1A1MAPT | |
| SCHEMBL9201579 | 0.91 | TRPM8 (0.38) | TDP1TAS2R14NR1H3MEN1KMT2A | |
| SCHEMBL9194700 | 0.89 | KMT2A (0.38) | TDP1EPHX1NR1H3ALDH1A1MAPT | |
| SCHEMBL9203185 | 0.89 | TDP1 (0.34) | TDP1MAPTCNR1CNR2HTT | |
| SCHEMBL9196838 | 0.89 | TDP1 (0.37) | TDP1ALDH1A1MAPTLMNACNR2 | |
| SCHEMBL9201326 | 0.88 | ALDH1A1 (0.37) | TDP1NR1H3ALDH1A1MAPTLMNA | |
| SCHEMBL9195755 | 0.88 | ALDH1A1 (0.37) | NR1H3ALDH1A1MAPTLMNAHPGD | |
| SCHEMBL9196808 | 0.87 | MAPT (0.33) | TDP1MAPTHTTNPSR1MEN1 | |
| SCHEMBL9195383 | 0.85 | NR3C2 (0.35) | TDP1NR1H3MEN1KMT2A | |
| SCHEMBL9198354 | 0.84 | KMT2A (0.32) | TDP1ALDH1A1MAPTGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | Dr. Karl Thomae GmbH (DE) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994017035-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1994-08-04 | — | — | WO | disclosed |