Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9195755 | 0.94 | ALDH1A1 (0.37) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL9198354 | 0.89 | KMT2A (0.32) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL9194668 | 0.88 | TDP1 (0.39) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL9201579 | 0.87 | TRPM8 (0.38) | MEN1KMT2ATDP1NR1H3 | |
| SCHEMBL9199475 | 0.86 | KMT2A (0.36) | MAPTMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL9203185 | 0.85 | TDP1 (0.34) | MAPTMEN1KMT2ATDP1HTT | |
| SCHEMBL9196808 | 0.83 | MAPT (0.33) | MAPTMEN1KMT2ATDP1HTT | |
| SCHEMBL9196838 | 0.83 | TDP1 (0.37) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL9195772 | 0.81 | EPHX1 (0.38) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL9195383 | 0.80 | NR3C2 (0.35) | MEN1KMT2ATDP1NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | Dr. Karl Thomae GmbH (DE) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994017035-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1994-08-04 | — | — | WO | disclosed |